@article{MRA, author = {Vaneeta Sheth and Sujeeta Silwal}, title = { Validation of VitBOD, a simple burden of disease instrument for vitiligo}, journal = {Medical Research Archives}, number = {3}, year = {2015}, keywords = {vitiligo; quality of life; burden of disease; mental health}, abstract = {Background: Vitiligo is a chronic, progressive condition of skin depigmentation that has a negative impact on quality of life. Aim of the study:  To validate a novel, low-burden tool to more accurately assess the burden of disease on those affected. Methods: The VitBOD was designed as a ten question tool using visual analog scales to assess various physical, mental and emotional domains of health specific to vitiligo.  90 subjects with dermatologist-confirmed vitiligo agreed to complete the self-administered VitBOD questionnaire along with the previously validated Short Form-36 (SF-36). Results: 67 fully completed questionnaires were returned.  VitBOD scores were transformed to fit the direction of the SF-36 for statistical analysis.  Median overall scores were significantly lower for VitBOD as shown by the paired t-test (75.3 vs 85, p=0.015).  VitBOD showed high internal consistency (Cronbach’s alpha = 0.9).  Vitality, social, and mental health domains correlated positively with SF-36. Conclusion: VitBOD can reliably measure burden of disease in vitiligo as well as the SF-36 with distinct advantages being ease and speed of use along with disease-specificity.  Testing in broader patient populations would be useful for further validation. }, issn = {2375-1924}, url = {https://esmed.org/MRA/mra/article/view/123} }