%A Hajsadeghi, Shokoufeh %A Bagheri, Yaghoub %A Manteghi, Mohammad Javad %A Firouzi, Ata %A Jafarian Kerman, Scott Reza %A Hassanzadeh, Morteza %D 2017 %T B-type natriuretic peptide and renovascular hypertension; is there any relation? %K BNP, Hypertension, Renal artery stenosis, Angioplasty %X Renal artery stenosis (RAS) is the most prevalent cause of secondary hypertension (HTN). Percutaneous trans-luminal renal angioplasty (PTRA) is used for both diagnosis and treatment of RAS. As many as one third of RAS cases fail to demonstrate post-PTRA HTN improvement. In this study, brain natriuretic peptide (BNP) was measured for consecutive patients with refractory HTN referred for renal artery angiography and 2 groups of participants (essential HTN and RAS) were compared. BNP was found significantly higher among RAS group than those with essential HTN ( P <0.001) and had a good sensitivity (76%) to discriminate RAS from essential HTN. RAS cases also showed a statistically significant decline in BNP level ( P <0.001) after PTRA. We concluded that BNP is increased in RAS before intervention, is declined after PTRA, and might be used both as a marker for discriminating RAS from essential refractory HTN and for post-PTRA follow-up. %U https://esmed.org/MRA/mra/article/view/1376 %J Medical Research Archives %0 Journal Article %V 5 %N 6 %@ 2375-1924 %8 2017-06-15