TY - JOUR AU - Hajsadeghi, Shokoufeh AU - Bagheri, Yaghoub AU - Manteghi, Mohammad Javad AU - Firouzi, Ata AU - Jafarian Kerman, Scott Reza AU - Hassanzadeh, Morteza PY - 2017/06/15 TI - B-type natriuretic peptide and renovascular hypertension; is there any relation? JF - Medical Research Archives; Vol 5 No 6 (2017): Vol.5 Issue 6, June, 2017 KW - BNP, Hypertension, Renal artery stenosis, Angioplasty N2 - Renal artery stenosis (RAS) is the most prevalent cause of secondary hypertension (HTN). Percutaneous trans-luminal renal angioplasty (PTRA) is used for both diagnosis and treatment of RAS. As many as one third of RAS cases fail to demonstrate post-PTRA HTN improvement. In this study, brain natriuretic peptide (BNP) was measured for consecutive patients with refractory HTN referred for renal artery angiography and 2 groups of participants (essential HTN and RAS) were compared. BNP was found significantly higher among RAS group than those with essential HTN ( P <0.001) and had a good sensitivity (76%) to discriminate RAS from essential HTN. RAS cases also showed a statistically significant decline in BNP level ( P <0.001) after PTRA. We concluded that BNP is increased in RAS before intervention, is declined after PTRA, and might be used both as a marker for discriminating RAS from essential refractory HTN and for post-PTRA follow-up. UR - https://esmed.org/MRA/mra/article/view/1376