@article{MRA, author = {PJ Steinkamp and van Zant F.A. and Hentzen J.E.K.R. and van G.M. and Kruijff S.}, title = { Improving visualization of colorectal metastatic cancer using laparoscopic fluorescence-guided surgery}, journal = {Medical Research Archives}, volume = {8}, number = {9}, year = {2020}, keywords = {}, abstract = {Extensive surgical treatment for peritoneal metastases originating from colorectal cancer provokes high morbidity and perioperative mortality rates, therefore careful and objective patient selection prior to such a procedure is crucial. Tumor-specific fluorescence-guided laparoscopy is a potential imaging technique for the improvement of patient selection. The aim is to select the patient that benefits the most of extensive and valuable surgical treatment, in terms of disease-free survival, overall survival and quality of life. Cancer-upregulated proteins and tumor-specific biological processes with matching fluorescence imaging agents could guide the surgeon to improved identification of malignant tissue during diagnostic laparoscopy and for detection of non-visible small tumor lesions during cytoreductive surgery.}, issn = {2375-1924}, doi = {10.18103/mra.v8i9.2233}, url = {https://esmed.org/MRA/mra/article/view/2233} }