@article{MRA, author = {Gerhard Zugmaier and Franco Locatelli}, title = { Application of Mathematical Logic for Cytogenetic Definition and Risk Stratification of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)}, journal = {Medical Research Archives}, volume = {9}, number = {2}, year = {2021}, keywords = {}, abstract = {BCP ALL is the most common phenotype of ALL.  Identification of recurrent genetic abnormalities specific for BCP-ALL [i.e., t(12;21), t(17;19), t(1;19)], has become an essential tool for confirmation of diagnosis and risk stratification. It can also be used for assessing response to treatment and for detecting the re-emergence of malignant cells. Although the definition of BCP ALL with recurrent genetic abnormalities can be correctly expressed in verbal terms, Mathematical Logic may provide a definition that is more concise. We defined the semantics of conjunctions by the truth values “1” or “0”. In a simplified syntax of English, the conjunctions “and”, “or”, “if and only if” were replaced by the symbols “∧ “, “V”, “↔” respectively. This method permitted definitions stripped from all ambiguous elements.}, issn = {2375-1924}, doi = {10.18103/mra.v9i2.2328}, url = {https://esmed.org/MRA/mra/article/view/2328} }