TY - JOUR AU - Ghosh, Ritwik AU - Roy, Dipayan AU - Ray, Adrija AU - Das, Shambaditya AU - Mandal, Amrita AU - Das, Shambaditya AU - Pal, Shyamal Kanti AU - Benito-León, Julián PY - 2022 TI - Non-Aneurysmal Subarachnoid Hemorrhage in COVID-19: A Case Report and Review of Literature JF - Medical Research Archives; Vol 10 No 1 (2022): Vol.10 Issue 1, January, 2022 DO - 10.18103/mra.v10i1.2673 KW - N2 - Background: Hemorrhagic cerebrovascular events, either due to aneurysmal rupture or spontaneous subarachnoid hemorrhage (SAH), are not rare in COVID-19. Several mechanisms such as coagulopathy, cytokine storm, viral endotheliopathy, hypertension, and immune modulation might play a role in the pathogenesis of SAH in COVID-19. This study aimed to report the first case of spontaneous non-aneurysmal SAH associated with SARS-CoV-2 from India. We briefly discussed the possible pathogenetic mechanisms underlying this process and succinctly reviewed the relevant literature. Case report: We herein report a case of a non-comorbid young woman infected with SARS-CoV-2 presenting with thunderclap headache and eventually non-aneurysmal SAH,  who recovered with conservative management. Conclusion: Headache, although a very common clinical feature of COVID-19 itself, must be investigated in detail to identify alternate causes that may be life-threatening. This case also incites further enquiry into the possible pathogenic mechanisms of neurovascular complications in COVID-19. UR - https://esmed.org/MRA/mra/article/view/2673