%A Telang, Nitin T. %D 2022 %T Cancer Stem Cells: Innovative Approach for Testable Alternatives against Therapy Resistant Cancer %K %X Chemo-resistant cancer stem cells represent a sub-population of cancer initiating phenotype in primary cancer. These cells evolve in to a metastatic phenotype via activation of multiple cell signaling pathways for cancer cell survival and epithelial-mesenchymal transition. Reliable cancer stem cell models represent a valuable experimental approach for drug discovery platform to identify efficacious testable alternatives against therapy-resistant cancer. Present commentary provides a systematic discussion of relevant conceptual and technical aspects of cancer stem cell biology and its significance for therapeutic alternatives.       %U https://esmed.org/MRA/mra/article/view/2968 %J Medical Research Archives %0 Journal Article %R 10.18103/mra.v10i8.2968 %V 10 %N 8 %@ 2375-1924 %8 2022-08-18