TY - JOUR AU - Kumar, Prathap AU - Jino, Blessvin AU - Rajendran, Manu PY - 2022 TI - Zero Contrast Percutaneous Coronary Intervention – A novel approach to reduce Contrast Induced Acute Kidney Injury JF - Medical Research Archives; Vol 10 No 12 (2022): December issue, Vol.10 Issue 12 DO - 10.18103/mra.v10i12.3264 KW - N2 - Iodinated contrast media are required in all cases who undergo coronary angiography and percutaneous coronary interventions (PCI). Though the modern contrast media (both low-osmolar and iso-osmolar) have lesser adverse effects than the older generation contrast media, they may lead to life threatening complications in few cases. Contrast induced acute kidney injury (CI-AKI) is one such complication where the presentation may vary from asymptomatic mild elevation in serum creatinine to life threatening uremia. Various pre-procedural and procedural steps are followed commonly to prevent CI-AKI and reducing the contrast volume is one of the most important steps. Indeed, multiple studies have proven that reducing the contrast volume during PCI reduces the risk of CI-AKI. More recently, intra-coronary imaging guided zero-contrast PCI has emerged as an important method to prevent CI-AKI. Though randomised controlled trials comparing low-contrast PCI and zero-contrast PCI are lacking, this technique is being used widely by experienced operators. Technical expertise in complex PCI and meticulous analysis of intra-coronary imaging, particularly intravascular ultrasound (IVUS), are mandatory for this procedure. UR - https://esmed.org/MRA/mra/article/view/3264