@article{MRA, author = {Robert Friedberg and Callie Goodman and Ellison Choate and Hannah Zelcer and Eunice Mendez and Yasaman Movahedi and Sandra Trafalis and Isabella Xie and Megan Neelly and Joee Zucker}, title = { Intolerance of uncertainty in pediatric patients: A transdiagnostic pathway to multiple disorders}, journal = {Medical Research Archives}, volume = {10}, number = {11}, year = {2022}, keywords = {}, abstract = {The search for transdiagnostic pathways and processes to emotional disorders in youth is an emerging and compelling field. In this mini-review, intolerance of uncertainty is posed as a transdiagnostic pathway. The theoretical foundation of intolerance of uncertainty is discussed. Subtypes of intolerance of uncertainty are explained, a behavioral typology is reviewed, neuropsychological correlates are briefly discussed, and age differences are addressed. The role of the Coronavirus-19 pandemic as a critical incident is examined. Subsequently, the research supporting the association between intolerance of uncertainty and anxiety, obsessive-compulsive,, depression, autism, as well as eating disorders is reviewed. The findings are then integrated into a parsimonious theoretical synthesis. Limitations of the research are delineated and clinical implications are presented   Key Words: Intolerance of uncertainty, transdiagnostic, anxiety, depression, autism, eating disorders}, issn = {2375-1924}, doi = {10.18103/mra.v10i11.3314}, url = {https://esmed.org/MRA/mra/article/view/3314} }