@article{MRA, author = {Kenneth Blum and Mark Gold and Jean Cadet and Marjorie Gondre-Lewis and Thomas McLaughlin and Eric Braverman and Igor Elman and B. Carney and Rene Cortese and Tomilowo Abijo and Debasis Bagchi and John Giordano and Catherine Dennen and David Baron and Panayotis Thanos and Diwanshu Soni and Milan Makale and Miles Makale and Kevin Murphy and Nicole Jafari and Keerthy Sunder and Foojan Zeine and Mauro Ceccanti and Abdalla Bowirrat and Rajendra Badgaiyan}, title = { Invited Expert Opinion- Bio-informatic and Limitation Di-rectives to Help Adopt Ge-netic Addiction Risk Screening and Identify Preaddictive Reward Dysregulation: Re-quired Analytic Evidence to Induce Dopamine Homeo-statsis}, journal = {Medical Research Archives}, volume = {11}, number = {8}, year = {2023}, keywords = {}, abstract = {Addiction, albeit some disbelievers like Mark Lewis [1], is a chronic, relapsing brain disease, resulting in unwanted loss of control over both substance and non- substance behavioral addictions leading to serious adverse consequences [2]. Addiction scientists and clinicians face an incredible challenge in combatting the current opioid and alcohol use disorder (AUD) pandemic throughout the world. Provisional data from the Centers for Disease Control and Prevention (CDC) shows that from July 2021-2022, over 100,000 individuals living in the United States (US) died from a drug overdose, and 77,237 of those deaths were related to opioid use [3]. This number is expected to rise, and according to the US Surgeon General it is highly conceivable that by 2025 approximately 165,000 Americans will die from an opioid overdose. Alcohol abuse, according to data from the World Health Organization (WHO), results in 3 million deaths worldwide every year, which represents 5.3% of all deaths globally [4].}, issn = {2375-1924}, doi = {10.18103/mra.v11i8.4211}, url = {https://esmed.org/MRA/mra/article/view/4211} }