@article{MRA, author = {A. Kaur and Aminder Singh and A. Singh and Harpreet Kaur and Bhavna Garg and Vikram Narang}, title = { Histopathological Spectrum of Cutaneous Lymphomas}, journal = {Medical Research Archives}, volume = {11}, number = {11}, year = {2023}, keywords = {}, abstract = {Background: Cutaneous lymphomas are a heterogeneous group of extra-nodal non-Hodgkin’s lymphomas that are characterized by a cutaneous infiltration of malignant monoclonal lymphocytes. Less frequently, these lymphomas spread from the skin to the blood or a lymph node. The incidence of primary cutaneous lymphoma has been estimated to be 1:100,000 according to the World Health Organization. Usually, these lymphomas affect adults with a median age of 50 to 60 years. T-cell lymphomas predominate over primary B-cell lymphomas of the skin. The most important subtypes of cutaneous T cell lymphomas are Mycosis fungoides, Sezary syndrome, and primary cutaneous peripheral T cell lymphomas not otherwise specified. These subtypes present different clinical, histological, and molecular features, and can follow an indolent or a very aggressive course. Aim: The aim of this study was to analyze cutaneous lymphomas to ascertain its clinical aspects including prevalence, histopathology and immune profile. Material and methods: A retrospective analysis of skin biopsies over a 7-year period ranging from 2016 to 2022 was done, of which 11 cases were diagnosed as cutaneous lymphomas. These cases were analyzed in detail including immune profile. Results & conclusions: The majority of the cases out of all cutaneous lymphomas were of T cell lymphoma and only one case was of B cell type. Definitive diagnosis of CTCL requires a multidisciplinary approach. Keywords: cutaneous T cell lymphoma, cutaneous B cell lymphoma.}, issn = {2375-1924}, doi = {10.18103/mra.v11i11.4712}, url = {https://esmed.org/MRA/mra/article/view/4712} }