@article{MRA, author = {Paul Goldwater and Reginald Gorczynski and Edward Steele}, title = { Sudden Infant Death Syndrome: A Review and Re-evaluation of Vaccination Risks}, journal = {Medical Research Archives}, volume = {13}, number = {3}, year = {2025}, keywords = {}, abstract = {Sudden infant death syndrome (SIDS) remains a leading cause of infant mortality. Medical science’s failure to elucidate its cause is opprobrious. SIDS shares many epidemiological traits with infectious diseases. Autopsy findings show very consistent findings in ~90% of cases, and immunological investigations consistently reveal underlying activation of inflammatory pathways. Surprisingly, most mainstream researchers have largely ignored these key findings.    The “Triple Risk Hypothesis” remains the mainstay for mainstream researchers. The hypothesis encompasses three main ideas: 1) a vulnerable infant, 2) a critical development period and 3) an exogenous stressor which combine lethally. Stressors include prone sleeping, smoke exposure, and overheating. Infections, though often overlooked, can trigger deadly immune responses. The COVID-19 pandemic and the use of parenterally administered SARS-Cov-2 vaccines provided an example of a lethal immunopathogenicity in elderly comorbid patients. During the pandemic, we reviewed papers on the impact of injected vaccines on infant mortality. The papers analysed vaccine adverse event reporting systems (VAERS) to conclude a possible causal relationship existed. It is of particular note that approximately 50% of cases in the VAERS dataset have been diagnosed as Sudden Infant Death Syndrome (SIDS). VAERS are known to capture a small minority of vaccine associated adverse events (estimated to be ~1%). Studies indicate that vaccination is preventative, but control groups often have more SIDS risk factors. The findings from the VAERS are of significant concern to the scientific, medical, public, and governmental communities. This review provides a scientific analysis of this apparent problem and proposes a case for vaccines that provide IgA-based mucosal immunity to replace (where appropriate) the potentially harmful parenterally administered vaccines currently in use. In addition to recommending the use of new safe vaccines, we highlight the role of breastfeeding in the prevention of sudden infant death syndrome (SIDS).}, issn = {2375-1924}, doi = {10.18103/mra.v13i3.6349}, url = {https://esmed.org/MRA/mra/article/view/6349} }