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01 · ABSTRACT

Abstract

Sudden infant death syndrome (SIDS) remains a leading cause of infant mortality. Medical science’s failure to elucidate its cause is opprobrious. SIDS shares many epidemiological traits with infectious diseases. Autopsy findings show very consistent findings in ~90% of cases, and immunological investigations consistently reveal underlying activation of inflammatory pathways. Surprisingly, most mainstream researchers have largely ignored these key findings.    The “Triple Risk Hypothesis” remains the mainstay for mainstream researchers. The hypothesis encompasses three main ideas: 1) a vulnerable infant, 2) a critical development period and 3) an exogenous stressor which combine lethally. Stressors include prone sleeping, smoke exposure, and overheating. Infections, though often overlooked, can trigger deadly immune responses. The COVID-19 pandemic and the use of parenterally administered SARS-Cov-2 vaccines provided an example of a lethal immunopathogenicity in elderly comorbid patients. During the pandemic, we reviewed papers on the impact of injected vaccines on infant mortality. The papers analysed vaccine adverse event reporting systems (VAERS) to conclude a possible causal relationship existed. It is of particular note that approximately 50% of cases in the VAERS dataset have been diagnosed as Sudden Infant Death Syndrome (SIDS). VAERS are known to capture a small minority of vaccine associated adverse events (estimated to be ~1%). Studies indicate that vaccination is preventative, but control groups often have more SIDS risk factors. The findings from the VAERS are of significant concern to the scientific, medical, public, and governmental communities. This review provides a scientific analysis of this apparent problem and proposes a case for vaccines that provide IgA-based mucosal immunity to replace (where appropriate) the potentially harmful parenterally administered vaccines currently in use. In addition to recommending the use of new safe vaccines, we highlight the role of breastfeeding in the prevention of sudden infant death syndrome (SIDS).

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02 · PUBLICATION RECORD

Article details

JournalMedical Research Archives
IssueVol 13 No 3 (2025): Vol.13, Issue 3, March 2025
SectionReview Articles
Published29 March 2025
DOI10.18103/mra.v13i3.6349
ISSN2375-1924
03 · RIGHTS & REUSE

Rights & reuse

The Medical Research Archives grants authors the right to publish and reproduce the unrevised contribution in whole or in part at any time and in any form for any scholarly non-commercial purpose with the condition that all publications of the contribution include a full citation to the journal as published by the Medical Research Archives.

 

Authors & affiliations

PG

Paul Nathan Goldwater

Adelaide Medical School, Faculty of Health and Medical Sciences, Adelaide University, Adelaide, SA, Australia.

RG

Reginald M. Gorczynski

Institute of Medical Science & Departments of Immunology and Surgery, University of Toronto, Canada.

ES

Edward J. Steele

Melville Analytics Pty Ltd and Immunomics, Brisbane, Australia.

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