Falciparum Malaria prevents HIV-associated Cervical Cancer in East and Central Africa (Hypothesis)

In many parts of the world the human immunodeficiency virus (HIV) and cervical cancer (CC) are associated, but four case-control studies from Mulago University Hospital, Kampala, a highly prevalent area of falciparum malaria  (FM), found no association. Adding to Kampala Tanzania and Rwanda with intermediate or low prevalence of FM and OR’s of 2.0 and 5.9, respectively, an inverse geographical distribution is noted. Similar to malariotherapy practised in Austria 120 years ago by injecting curable types of malaria HIV might be eliminated by more aggressive attacks of FM. Recently, experts proposed future research on HIV and cancer. Risks accounting for FM should be determined for HIV-associated CC.