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01 · ABSTRACT

Abstract

Objectives: This study is to investigate the effects of 3 functional food supplements on basic metabolic parameters on 61 healthy adult individuals. The 24-week study was completed with 43 men and 18 adult women. The average age of the participants was 30 ± 9 years.

Methods: In this study, anti-atherosclerotic liquid (AAL)-Morinda citrifolia (3 mL once per day orally) anti-inflammatory capsules (AIC)-Omega-3 (3 capsules once per day orally) extract with antioxidant liquid (AOL)- Blueberry and 21 different red purple fruit vegetables (30 mL once per day orally) have been used. We compared 24 weeks before and after.

Results: The study shows the longitudinal changes of selected parameters in the 61 healthy people that completed the study. Following anti-atherosclerotic liquid (AAL), anti-inflammatory capsules (AIC) and antioxidant liquid (AOL) therapies, asymmetric dimethylarginine (ADMA), malondialdehyde (MDA), pentraxin-3 (PTX3), homeostatic model assessment of insulin resistance (HOMA-IR), high-sensitivity C-reactive protein (hs-CRP), systolic blood pressure (SBP), diastolic blood pressure (DBP), glycated hemoglobin (HbA1c), body mass index (BMI), fasting plasma glucose (FPG), total cholesterol, and low-density lipoprotein cholesterol (LDL) levels were significantly decreased, while flow-mediated dilation (FMD), glutathione peroxidase (GSH-Px), high-density lipoprotein cholesterol (HDL), 25-hydroxyvitamin D (25OHVD), and folic acid levels were significantly increased.

Conclusions: Our results indicated that selected functional food supplements showed strong beneficial effect on selected metabolic parameters.

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02 · PUBLICATION RECORD

Article details

JournalMedical Research Archives
IssueVol 13 No 8 (2025): Vol.13, Issue 8, August 2025
SectionResearch Articles
Published25 August 2025
DOI10.18103/mra.v13i8.6826
ISSN2375-1924
03 · RIGHTS & REUSE

Rights & reuse

This article is published under a Creative Commons Attribution License (CC BY 3.0) and may be shared or distributed by anyone as long as attribution is given to the journal.

Authors & affiliations

ZD

Zeynep Demir

Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, USA

MD

Muhammet Fatih Demir

Wake Forest University, Center for Artificial Intelligence Research, Winston-Salem, NC, USA

NY

Nilgun Ece Yilmaz

Ankara Training and Research Hospital, Department of Emergency Medicine, Ankara, Turkey

AA

Awatif M. Abuzgaia

Division of Pediatric Rheumatology, Victoria Children’s Hospital, University of Western Ontario, London, ON, Canada

AE

Abdelbaset Elzagallaai

Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Canada

DP

David Piskin

Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Canada

MY

Murat Tolga Yilmaz

Environmental Engineering Department, Engineering Faculty, Atatürk University, Erzurum, Turkey

AS

Aysegul Elbir Sahin

Samsun Training and Research Hospital, Clinic of Anesthesiology and Reanimation, Samsun, Türkiye

Mustafa Öztürk

Private Medistate Hospital, Department of Oncology, Istanbul, Turkey

HD

Halit Demir

Van Yuzuncu Yil University, Department of Biochemistry, Van, Turkey.

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