Article Test

Home  >  Medical Research Archives  >  Issue 149  > A Glioblastoma Genomics Primer for Clinicians
Published in the Medical Research Archives
Feb 2020 Issue

A Glioblastoma Genomics Primer for Clinicians

Published on Feb 21, 2020




Abstract: New discoveries in Glioblastoma (GBM) biology have been made using genomics data.  Genomic markers are routinely integrated into clinical neurosurgical practice.  In this manuscript, we review fundamentals of genomics such as the differences between first, second, and third generation sequencing technology.  We also review the impact of single cell genomics in understanding the complex heterogenous GBM microenvironment.  Finally, we will discuss advances in epigenetics that have lent insights into treatment resistance. The integration of genomics into neuro-oncology clinical practice is routine and will continue to expand with the expansion of precision of medicine.  We provide a primer for clinicians.


Author info

John Patterson, Analiz Rodriguez, Thidathip Wongsurawat

Have an article to submit?

Submission Guidelines

Submit a manuscript

Become a member

Call for papers

Have a manuscript to publish in the society's journal?