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Background: The growing prevalence of overweight/obesity in patients with diabetes mellitus and hypertension has become a global health concern, which is increasing the risk of deaths. Knowing some factors leading to obesity allows more effective and appropriate prevention.

Aims: To identify some related factors to the nutritional status of patients with both type 2 diabetes mellitus and hypertension at the National hospital of Endocrinology in 2019-2020.

Methods: A cross-sectional study on 228 patients with type 2 Diabetes mellitus and hypertension at the National Hospital of Endocrinology from September 2019 to December 2019.

Results: The results revealed that the elderly group has a higher obesity rate than the middle-aged group (P<0.05). Overweight/obesity subjects had higher protein intake than those with Non-overweight/obesity (P<0.05). Unsatisfactory anthropometric indexes such as waist circumference (WC), waist-hip ratio (WHR), body fat percentage (BFP) had higher odds of overweight/obesity than those who have satisfactory index (OR=10.3, 18.4 and 13.5, respectively). Besides, 24-hours intake, eating habits and physical activity affected the risk of overweight/obesity. Lower frequency consumption of milk for diabetics and participation in physical activities had higher odds of overweight/obesity (OR=2.2, P<0.05). Conclusion: The body mass index of patients is associated with the anthropometric indexes, diets and physical activity.