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Home  >  Medical Research Archives  >  Issue 149  > Castleman Disease: A Wide Spectrum of Thoracic Manifestations
Published in the Medical Research Archives
Jun 2022 Issue

Castleman Disease: A Wide Spectrum of Thoracic Manifestations

Published on Jun 01, 2022

DOI 

Abstract

 

Castleman’s disease is a benign lymphoproliferative disorder affecting both lymph nodes and extranodal loci. Castleman’s disease can occur in practically any part of the body, but it occurs mainly in the thorax (~70%) followed by the abdomen and pelvis, neck and axilla. Clinically, Castleman’s disease can be classified into a unicentric or multicentric form, depending on the number of lymph nodes involved, and histologically into a hyaline vascular variant, plasma cell, mixed cellular or plasmablastic variant. In this mini-review we briefly report and focus on all clinical thoracic manifestations of Castleman’s disease resuming for each of them the possible strategy of treatment.

Author info

Giuseppe Mangiameli, Ugo Cioffi, Federica Carlea, Alberto Testori, Marco Alloisio

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