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In 2020 lung cancer has been the leading cause of cancer death, with an estimated 1.8 million deaths; in other words of 18% of cancer deaths. Tobacco smoking is cause of 90% of lung cancers. Despite advances in lung cancer treatment, tobacco control is the most effective measure for curbing the lung cancer epidemic. Smoking cessation, at all stages of the cancer process, is associated with benefits in terms of cure, increased life expectancy and quality of life for patients, reduced medical and surgical complications, as well as it reduces risks of recurrence or of a second primary cancer. Smoking cessation medications combined with psychological support facilitate to quit smoking. Smoking cessation management is an essential component of lung cancer treatment. Researches into the best modalities to manage smoking cessation in lung cancer patients must be conducted. Nevertheless, healthcare professionals involved in the care of cancer patients must be trained to provide personalized assistance to help smokers stopping smoking.