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With the rapid developments in the field of interstitial lung diseases or diffuse parenchymal lung diseases as it is now called, this review provides an overview of ILDs and explains the gamut of knowledge needed to understand the disease, starting from the anatomy of the interstitium to the causes of interstitial involvement in various diseases and the clinicoradiological patterns of involvement in various interstitial lung diseases. The review is in the format of questions and answers to make it easier for the resident to comprehend.