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Home  >  Medical Research Archives  >  Issue 149  > Treatments and new perspectives of Antiphospholipid Syndrome in pregnancy
Published in the Medical Research Archives
May 2018 Issue

Treatments and new perspectives of Antiphospholipid Syndrome in pregnancy

Published on May 18, 2018

DOI 

Abstract

 

Antiphospholipid syndrome (APS) is characterized by thrombosis and/or recurrent miscarriage and the presence of persistent antiphospholipid antibodies (aPL).  APS during pregnanvy represents an increased risk of miscarriage and thrombotic events for the woman and fetus. The treatment of APS is based on lifetime anticoagulation therapy, using aspirin which may be combined with heparin. However, many reports show that women can be refractory to this treatment. In spite of attempts to develop new therapies, the treatment outcomes for APS in pregnancy remain poor. The development of new therapeutic modalities is needed to treat and/or prevent thrombosis in pregnant patients with APS and protect the fetus.

Author info

Jan Carlo Delorenzi, Micael Cunha, Guilherme Vergara, Camila Mary

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