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In the absence of Federal safety standards for occupancy of buildings with a history of water intrusion, remediation of water-damaged buildings (WDB) has focused on building health issues, including correction of defects in the building envelope, microbial growth and removal of contaminated materials. To date, no guidelines have been published that incorporate human health parameters into professional recommendations regarding treatment of the potentially unsafe conditions found in WDB.This document is a consensus statement that expands on existing professional society recommendations by including guidelines for remediation of buildingsto be occupied by known, previously sickened patients.