Home > Medical Research Archives > Issue 149 > Cancer Stem Cells: Innovative Approach for Testable Alternatives against Therapy Resistant Cancer
Published in the Medical Research Archives
Aug 2022 Issue
Cancer Stem Cells: Innovative Approach for Testable Alternatives against Therapy Resistant Cancer
Published on Aug 18, 2022
DOI
Abstract
Chemo-resistant cancer stem cells represent a sub-population of cancer initiating phenotype in primary cancer. These cells evolve in to a metastatic phenotype via activation of multiple cell signaling pathways for cancer cell survival and epithelial-mesenchymal transition. Reliable cancer stem cell models represent a valuable experimental approach for drug discovery platform to identify efficacious testable alternatives against therapy-resistant cancer. Present commentary provides a systematic discussion of relevant conceptual and technical aspects of cancer stem cell biology and its significance for therapeutic alternatives.
Author info
Nitin Telang
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