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The cause of ischial sore is synovial bursa which is made of pressure or shear on the ischial bone. Because of this mechanism, ischial sore often has big subcutaneous pocket compared to its skin defect. To treat this ischial ulcer, complete pocket resection and reconstruction with appropriate flap is the popular way, but we could treat five relapsing ischial sores by applying PRP and direct closing. Ischial sores are often found on the buttock of paraplegia patients who keep sitting on wheel chairs long time. They have high possibility of recurrence of ischial sores as long as using wheel chairs. This method is useful for them because no normal tissues around sore is resected and possibility of using local flaps can be remained when sore relapse.