Essential thrombocythemia presenting with ischemic mitral regurgitation and recanalized coronary artery thrombosis: a case report.

Abstract

Essential thrombocythemia (ET) is a rare myeloproliferative disorder characterized by pathologic expansion of the megakaryocytic elements in the bone marrow leading to persistent thrombocytosis and platelet dysfunction. Coronary artery disease can occur in 9% of cases and there is a high incidence of acute myocardial infarction (MI). Here, a case of ET in a patient with re-canalized coronary artery thrombosis that presented with ischemic mitral regurgitation secondary to left ventricle dilatation and remodeling is reported. As there are no clear guidelines for best management approach to these patients when cardiac surgery is planned, we report the successful management of such a case. The patient had uneventful postoperative recovery following coronary artery bypass graft surgery and bioprosthetic mitral valve replacement.