Enhanced effects of paraprobiotics ( inactivated probiotics) and postbiotics ( probiotic growth end products ) on significantly improving therapeutic properties of drugs , nutraceuticals and dietary supplements .

This research relates to bio-affecting nutraceuticals, dietary supplements, and drugs which are activated with the inclusion of paraprobiotics along with their postbiotics. More specifically it relates to replacing probiotics, which are live, with the same efficacy using inactivated paraprobiotics along with their postbiotics. Some instances, the research further relate to intentional mixture of two or more paraprobiotics of different genera to enhance the efficacy of dietary supplements, nutraceuticals, and therapeutic drugs. It also relates to the use of nutraceuticals and dietary supplements to the improvement of certain aliments, and also pharmacotherapy (to treat or cure certain disease) in which the scope of medical preparations includes a range of pharmaceuticals include allopathic drugs, periodontal drugs, homeopathic drugs, Ayurvedic drugs, Siddha drugs, Unani drugs, and herbal drugs including but not limited to Chinese herbal medicines etc. The research results are serendipitous in that unexpectedly even the paraprobiotics along with their growth end products or postbiotics in combination with the drugs resulted in enhancing the drug efficiency to treat or cure the specific disease, without any side effects, proving that the probiotics do not have to be live to improve the drug efficiency. Similar observations were made to enhance the effect of nutraceuticals or dietary supplements by mixing with the paraprobiotics along with their growth end products. The results also revealed that due to inclusion of specific paraprobiotics along with the postbiotics with the nutraceuticals or dietary supplements or drugs to enhance their efficiency, resulted in using less amount of the nutraceutical or therapeutic dose intended either to support the health or treat a disease condition at much faster pace, without any adverse side effects. It is always good and preferred to reduce the amount of usage or dosage of drugs to eliminate their toxic effects. Such reduction in usage of the therapeutic drugs has been achieved serendipitously in the current research investigation.