Rare presentation of subcutaneous sarcoid granulomas: A case report and review of the literature

Abstract

BACKGROUND:  Few cases of Darier-roussey type sarcoidosis have ever been presented in the literature due to the rarity of this condition.  Sarcoidosis occurs in only 10-20 per 100, 000 in the population and can be present throughout various organs and sites of the body.  Skin manifestation as a broad category represent just 25-35% of these cases and even more rare is the Darier-roussey type which has not had prevalence quantified. 

METHODS: A systematic review of the literature was conducted using PubMed database and assistance from clinical staff to conduct keyword searches for ‘sarcoidosis”, “cutaneous sarcoidosis”, and “Darier-roussey sarcoidosis”.  The search results were reviewed by the authors and selected based on the relevance to the case report presented.

CONCLUSIONS: There is extensive literature relating to sarcoidosis but sparse case reports relating to Darier-roussey type.  We found only 5 some dating back to the year 1930.  This presentation through process of elimination was determined to be sarcoidosis presenting in the rare form as Darier-roussey and it is our hope that by adding to the literature a modern case reported we can improve the understanding of this disease presentation and successful treatment with steroid therapy.