Biophysical model of active transport through vesicles

Main Article Content

Janos Vincze Gabriella Vincze-Tiszay


The transport phenomena in the human organism mean the variation in time and space of generalized forces when they generate flows for which conservation laws apply. The more specific transport mechanisms are following: ion pump, transporting molecules, ionic channels and active transport through vesicles. The process of cytopempsis, or the process of transport via the vesicles, is also a vesicular process, initiated in the membrane area. The vesicle in this case constitutes a means of transport of the substances through cell, the contents of the vesicle as a whole being transported through the cytoplasm, and then released. Endocytosis consists of the transport of substances from the extracellular environment to the interior of the cell with the help of a vesicle formed by the cell membrane. Exocytosis is the process by which the fusion of some vesicles of the cytoplasm with the cell membrane is produced being followed by the expulsion of the vesicle content outside the cell. The pattern of the pinocytosis considers its static character, that is the probability to form vesicles. This mathematical model, is applicable from all active transport through vesicles.

Article Details

How to Cite
VINCZE, Janos; VINCZE-TISZAY, Gabriella. Biophysical model of active transport through vesicles. Medical Research Archives, [S.l.], v. 8, n. 4, apr. 2020. ISSN 2375-1924. Available at: <>. Date accessed: 25 oct. 2021. doi:
Research Articles


[1] J. Vincze, Caracterization of Transport Processes in Living Systems. in Proceeding of the Regional of the IUPS, 265–266, 1970.
[2] B. Hille, Ionic channels of excitable membrane, Sinauer, Sunderland, MA, 1984.
[3] M.H. Friedman, Principles and Models of Biological Transport, Springer-Verlag, Berlin Heidelberg New York Tokyo, 1986.
[4] J. E. Hall, Guyton and Hall Textbock of Medical Physiology, (12th Edition) Elsevier, Philadelphia, 2011.
[5] X. L. Huang, H. L. Tang, Z. G. Cheu, T. Zhon, and K. Sun, Peripherial invariant in metabolism, The Journal of International Medical Research, vol. 44. pp. 1272–1282, 2016.
[6] A. Di, and A.B. Malik, „TRP channeles and the control of vascular function.” Curent Opinion in Pharmacology vol. 10, pp. 127–132, 2010.
[7] W. D. Stein, Them movement of molecules across cell membranes, Academic Press, New York, 1967.
[8] J. Vincze, Z. Vincze, „The Mathematical Model of the Endocytosis”, Acta Biologica Debrecina Suppl. pp. 25–31, 1991.
[9] E. N. Lightfott, Transport phenomena in medicine and living systems, Wiley, 1974.
[10] J. Vincze, The Transport Phenomena and Cross-effects in the Living Systems, Second Edition, NDP P., Budapest, 2017.
[11] W. D. Stein, Them movement of molecules across cell membranes, Academic Press, New York, 1967.
[12] J. Vincze, Medical Biophysics, NDP P., Budapest, 2018.

Most read articles by the same author(s)