Backgrounds of Computer-Aided Assessment of Morphological Structure in Polymer Drugs-Delivery Microcapsules

Main Article Content

Juliusz L. Kulikowski,, DSc

Abstract

Microcapsules are widely used as one of the drug delivery means.  The paper presents the backgrounds of a method of microcapsules size and shape assessment by computer-aided analysis of microscope images of microcapsules’ cross-sections. The method has been elaborated and is practically used to the microcapsules quality control at the Nalecz Institute of Biocybernetics and Biomedical Engineering PAS in Warsaw. Mathematical definitions of parameters describing the size, shape and inner structure of microcapsules are described in the paper. A general scheme of a computer-aided microcapsules quality assessment procedure is presented. Remarks about the limitations of the applicability of the described microcapsules assessment method are also given. On this basis, directions of future works aimed at improvement of the described microcapsules quality assessment method are suggested.

Keywords: drugs delivery, microcapsules, computer- aided image analysis, irregular shape approximation, microcapsules quality assessment

Article Details

How to Cite
KULIKOWSKI,, Juliusz L.. Backgrounds of Computer-Aided Assessment of Morphological Structure in Polymer Drugs-Delivery Microcapsules. Medical Research Archives, [S.l.], v. 9, n. 2, feb. 2021. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/2312>. Date accessed: 22 dec. 2024. doi: https://doi.org/10.18103/mra.v9i2.2312.
Section
Research Articles

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