Long Term Volume Survival after Autologous Fat Transplantation to the Breast: A Review
Main Article Content
Abstract
Importance
Autologous fat transplantation for breast augmentation has become a standard technique and is widely applied. The major weak point is that long time results, especially sudies about long term volumetric survival of the fat grafts have not been available yet.
Observations
We compared the available literature about volume survival after fat transplantation, including recent findings six years after fat transfer to the breast, showing stable results and even volume gain of transplanted fat grafts in patients that gained weight.
Conclusions
Fat transplantation to the breast for cosmetic breast augmentation offers stable long term results in terms of volume survival of the transplanted fat grafts. The available long term studies do not show any late complications of fat transfer.
Keywords:
fat transplantation, lipofilling, volume survival, 3 D volumetry, MRI volumetry, breast augmentation
Article Details
How to Cite
HEROLD, C..
Long Term Volume Survival after Autologous Fat Transplantation to the Breast: A Review.
Medical Research Archives, [S.l.], v. 9, n. 3, mar. 2021.
ISSN 2375-1924.
Available at: <https://esmed.org/MRA/mra/article/view/2360>. Date accessed: 26 apr. 2024.
doi: https://doi.org/10.18103/mra.v9i3.2360.
Section
Research Articles
The Medical Research Archives grants authors the right to publish and reproduce the unrevised contribution in whole or in part at any time and in any form for any scholarly non-commercial purpose with the condition that all publications of the contribution include a full citation to the journal as published by the Medical Research Archives.
References
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8. Ueberreiter K, Von Finckenstein JG, Cromme F, Herold C, Tanzella U, Vogt PM. BEAULI – Eine neue Methode zur einfachen und zuverlässigen Fettzell-Transplantation. Handchirurgie Mikrochirurgie Plast Chir 2010; 42: 379–385.
9. Delay E, Garson S, Tousson G, Sinna R. Fat injection to the breast: technique, results, and indications based on 880 procedures over 10 years. Aesthet Surg J 2009;29: 360-376.
10. Spear SL, Pittman T. A prospective study on lipoaugmentation of the breast. Aesthetic Surg J 2014; 34: 400–408.
11. Khouri RK, Khouri RK, Rigotti G, Marchi A, Cardoso E, Rotemberg SC, Biggs TM.
Aesthetic Applications of Brava-Assisted Megavolume Fat Grafting to the Breasts. A 9-Year, 476-Patient, Multicenter Experience Plast Reconstr Surg 2014; 133: 796–807.
12. Long-term evaluation after autologous fat transplantation for breast augmentation.
Ueberreiter CS, Ueberreiter K, Mohrmann C, Herm J, Herold C. Handchir Mikrochir Plast Chir. 2020 Aug 10 e-pub ahead of print
13. Hussain Z, Roberts N, Whitehouse GH, García-Fiñana M, Percy D. Estimation of breast volume and its variation during the menstrual cycle using MRI and stereology. Br J Radiol 1999; 72: 236–245.
14. Peltoniemi HH, Salmi A, Miettinen S, Mannerström B, Saariniemi K, Mikkonen R,
Kuokkanen H, Herold C. Stem cell enrichment does not warrant a higher graft survival in lipofilling of the breast: A prospective comparative study. J Plast Reconstr Aesthet Surg 2013; 66: 1494–1503.
15. Peltoniemi HH, Salmi A, Saariniemi K, Kuokkanen H, Herold C. Enrichment with Adipose-Derived Stem Cells Does Not Enhance Water-Jet Fat Graft Survival in the Breast—A Prospective Comparative Study. Surg Sci 2016; 07: 485–495.
16. Yoshimura K, Sato K, Aoi N, Kurita M, Hirohi T, Harii K. Cell-Assisted Lipotransfer for Cosmetic Breast Augmentation: Supportive Use of Adipose-Derived Stem/Stromal Cells. Aesthetic Plast Surg 2008; 32: 48–55.
17. Laloze J, Varin A, Gilhodes J, Bertheuil N, Grolleau JL, Brie J, Usseglio J, Sensebe L, Filleron T, Chaput B. Cell-assisted lipotransfer: Friend or foe in fat grafting? Systematic review and meta-analysis. J Tissue Eng Regen Med 2018; 12: e1237–e1250.
18. Del Vecchio DA, Bucky LP. Breast augmentation using preexpansion and autologous fat transplantation: a clinical radiographic study.. Plast Reconstr Surg. 2011 Jun;127(6):2441-50
19. Glovinski P V., Herly M, Müller FC, Elberg JJ, Kølle S-FT, Fischer-Nielsen A, Thomsen C, Drzewiecki KT. Avoiding a Systematic Error in Assessing Fat Graft Survival in the Breast with Repeated Magnetic Resonance Imaging. Plast Reconstr Surg - Glob Open 2016; 4: e1023
20. Khouri RK, Eisenmann-Klein M, Cardoso E, Cooley BC, Kacher D, Gombos E, Baker TJ. Brava and autologous fat transfer is a safe and effective breast augmentation alternative: results of a 6-year, 81-patient, prospective multicenter study. Plast Reconstr Surg. 2012 May;129(5):1173-1187
21. Fiaschetti V, Pistolese CA, Fornari M, Liberto V, Cama V, Gentile P, Floris M, Floris R, Cervelli V, Simonetti G. Magnetic resonance imaging and ultrasound evaluation after breast autologous fat grafting combined with platelet-rich plasma. Plast Reconstr Surg 2013; 132: 498–509.
22. Gentile P, Di Pasquali C, Bocchini I, Floris M, Eleonora T, Fiaschetti V, Floris R, Cervelli Breast reconstruction with autologous fat graft mixed with platelet-rich plasma.V.Surg Innov. 2013 Aug;20(4):370-6. doi: 10.1177/1553350612458544. Epub 2012 Sep 10.
23. Dos Anjos S, Matas-Palau A, Mercader J, Katz AJ, Llull R. Reproducible Volume Restoration and Efficient Long-term Volume Retention after Point-of-care Standardized Cell-enhanced Fat Grafting in Breast Surgery. Plast Reconstr Surg Glob Open. 2015 Oct 23;3(10):e547.
24. Ho Quoc C, Taupin T, Guérin N, Delay E. Volumetric evaluation of fat resorption after breast lipofilling. Ann Chir Plast Esthet. 2015 Dec;60(6):495-9
25. Chiu CH. Does Stromal Vascular Fraction Ensure a Higher Survival in Autologous Fat Grafting for Breast Augmentation? A Volumetric Study Using 3-Dimensional Laser Scanning. Aesthet Surg J. 2019 Jan 1;39(1):41-52
2. Spear SL, Murphy DK, Allergan Silicone Breast Implant U.S. Core Clinical Study Group. Natrelle Round Silicone Breast Implants. Plast Reconstr Surg 2014; 133: 1354–1361.
3. Headon H, Kasem A, Mokbel K. Capsular Contracture after Breast Augmentation: An Update for Clinical Practice. Arch Plast Surg 2015; 42: 532.
4. Horl HW, Feller AM, Biemer E. Technique for liposuction fat reimplantation and long-term volume evaluation by magnetic resonance imaging. Ann Plast Surg 1991;26: 248-258.
5. Herold C, Ueberreiter K, Busche MN, Vogt PM. Autologous fat transplantation: volumetric tools for estimation of volumesurvival. A systematic review. Aesthetic Plast Surg. 2013 Apr;37(2):380-7
6. Herold C, Knobloch K, Rennekampff HO, Ueberreiter K, Vogt PM Magnetic resonance imaging-based progress control after autologous fat transplantation. Plast Reconstr Surg. 2010 Nov;126(5):260e-261e.
7. Herold C, Ueberreiter K, Cromme F, Busche MN, Vogt PM. [The use of mamma MRI volumetry to evaluate the rate of fat survival after autologous lipotransfer]. MRT-Volumetrie der Mamma zur Kontrolle der Fettresorptionsrate nach autologem Lipotransfer 2010; 42: 129–134.
8. Ueberreiter K, Von Finckenstein JG, Cromme F, Herold C, Tanzella U, Vogt PM. BEAULI – Eine neue Methode zur einfachen und zuverlässigen Fettzell-Transplantation. Handchirurgie Mikrochirurgie Plast Chir 2010; 42: 379–385.
9. Delay E, Garson S, Tousson G, Sinna R. Fat injection to the breast: technique, results, and indications based on 880 procedures over 10 years. Aesthet Surg J 2009;29: 360-376.
10. Spear SL, Pittman T. A prospective study on lipoaugmentation of the breast. Aesthetic Surg J 2014; 34: 400–408.
11. Khouri RK, Khouri RK, Rigotti G, Marchi A, Cardoso E, Rotemberg SC, Biggs TM.
Aesthetic Applications of Brava-Assisted Megavolume Fat Grafting to the Breasts. A 9-Year, 476-Patient, Multicenter Experience Plast Reconstr Surg 2014; 133: 796–807.
12. Long-term evaluation after autologous fat transplantation for breast augmentation.
Ueberreiter CS, Ueberreiter K, Mohrmann C, Herm J, Herold C. Handchir Mikrochir Plast Chir. 2020 Aug 10 e-pub ahead of print
13. Hussain Z, Roberts N, Whitehouse GH, García-Fiñana M, Percy D. Estimation of breast volume and its variation during the menstrual cycle using MRI and stereology. Br J Radiol 1999; 72: 236–245.
14. Peltoniemi HH, Salmi A, Miettinen S, Mannerström B, Saariniemi K, Mikkonen R,
Kuokkanen H, Herold C. Stem cell enrichment does not warrant a higher graft survival in lipofilling of the breast: A prospective comparative study. J Plast Reconstr Aesthet Surg 2013; 66: 1494–1503.
15. Peltoniemi HH, Salmi A, Saariniemi K, Kuokkanen H, Herold C. Enrichment with Adipose-Derived Stem Cells Does Not Enhance Water-Jet Fat Graft Survival in the Breast—A Prospective Comparative Study. Surg Sci 2016; 07: 485–495.
16. Yoshimura K, Sato K, Aoi N, Kurita M, Hirohi T, Harii K. Cell-Assisted Lipotransfer for Cosmetic Breast Augmentation: Supportive Use of Adipose-Derived Stem/Stromal Cells. Aesthetic Plast Surg 2008; 32: 48–55.
17. Laloze J, Varin A, Gilhodes J, Bertheuil N, Grolleau JL, Brie J, Usseglio J, Sensebe L, Filleron T, Chaput B. Cell-assisted lipotransfer: Friend or foe in fat grafting? Systematic review and meta-analysis. J Tissue Eng Regen Med 2018; 12: e1237–e1250.
18. Del Vecchio DA, Bucky LP. Breast augmentation using preexpansion and autologous fat transplantation: a clinical radiographic study.. Plast Reconstr Surg. 2011 Jun;127(6):2441-50
19. Glovinski P V., Herly M, Müller FC, Elberg JJ, Kølle S-FT, Fischer-Nielsen A, Thomsen C, Drzewiecki KT. Avoiding a Systematic Error in Assessing Fat Graft Survival in the Breast with Repeated Magnetic Resonance Imaging. Plast Reconstr Surg - Glob Open 2016; 4: e1023
20. Khouri RK, Eisenmann-Klein M, Cardoso E, Cooley BC, Kacher D, Gombos E, Baker TJ. Brava and autologous fat transfer is a safe and effective breast augmentation alternative: results of a 6-year, 81-patient, prospective multicenter study. Plast Reconstr Surg. 2012 May;129(5):1173-1187
21. Fiaschetti V, Pistolese CA, Fornari M, Liberto V, Cama V, Gentile P, Floris M, Floris R, Cervelli V, Simonetti G. Magnetic resonance imaging and ultrasound evaluation after breast autologous fat grafting combined with platelet-rich plasma. Plast Reconstr Surg 2013; 132: 498–509.
22. Gentile P, Di Pasquali C, Bocchini I, Floris M, Eleonora T, Fiaschetti V, Floris R, Cervelli Breast reconstruction with autologous fat graft mixed with platelet-rich plasma.V.Surg Innov. 2013 Aug;20(4):370-6. doi: 10.1177/1553350612458544. Epub 2012 Sep 10.
23. Dos Anjos S, Matas-Palau A, Mercader J, Katz AJ, Llull R. Reproducible Volume Restoration and Efficient Long-term Volume Retention after Point-of-care Standardized Cell-enhanced Fat Grafting in Breast Surgery. Plast Reconstr Surg Glob Open. 2015 Oct 23;3(10):e547.
24. Ho Quoc C, Taupin T, Guérin N, Delay E. Volumetric evaluation of fat resorption after breast lipofilling. Ann Chir Plast Esthet. 2015 Dec;60(6):495-9
25. Chiu CH. Does Stromal Vascular Fraction Ensure a Higher Survival in Autologous Fat Grafting for Breast Augmentation? A Volumetric Study Using 3-Dimensional Laser Scanning. Aesthet Surg J. 2019 Jan 1;39(1):41-52