History of Trypanosomosis in the One-Humped Camel and Development of its Treatment and Cure, with Special Reference to Sudan
Main Article Content
Abstract
Sudan has one of the largest populations of domestic animals in Africa. One-humped camel (Camelus dromedarius) numbers were estimated at 4.5 million in 2009. Once used extensively for military transport they are still used in the transport role by spatially mobile pastoralist households and are a major source of milk and meat for these people. Trypanosomosis, due to Trypanosoma evansi, generally known as ‘surra’ but as ‘gufar’ in Sudan was first identified in camels in the country in 1902 and is the main cause of disease although T. vivax infections have recently been discovered in parts of Sudan. This protozoan disease is the most important health problem in camels, causing high morbidity and huge production losses. The causal organism, unlike most other trypanosomes, is not transmitted cyclically with tsetse (genus Glossina) flies as the vector but mechanically by biting flies mainly family Tabanidae but also by others of the Muscidae. Identification of the parasite in camel blood was initially by simple microscopic techniques but biotechnology and molecular methods now enable infection to be diagnosed at an earlier stage and with more accuracy. Prophylactic and curative treatments of trypanosomosis are notoriously complicated and uncertain with the situation in camels being exacerbated because of its peculiar physiology. Many trypanocides have been developed over time but the parasite often develops resistance to these drugs. Some drugs are successful, for some time, as both prophylactics and cures but are often accompanied by undesirable side effects. Other drugs used on conventional domestic stock are ineffective in camels or have lower efficacy. Research on diagnosis and treatment of trypanosomosis is continuing but the disease continues to cause production losses to the detriment of national and household incomes and food security.
Keywords:
Trypanosoma evansi, Trypanosoma vivax, Camelus dromedarius, 'surra’, prophylaxis, trypanocides
Article Details
How to Cite
WILSON, R Trevor; DIOLI, Maurizio.
History of Trypanosomosis in the One-Humped Camel and Development of its Treatment and Cure, with Special Reference to Sudan.
Medical Research Archives, [S.l.], v. 9, n. 7, july 2021.
ISSN 2375-1924.
Available at: <https://esmed.org/MRA/mra/article/view/2513>. Date accessed: 22 nov. 2024.
doi: https://doi.org/10.18103/mra.v9i7.2513.
Section
Research Articles
The Medical Research Archives grants authors the right to publish and reproduce the unrevised contribution in whole or in part at any time and in any form for any scholarly non-commercial purpose with the condition that all publications of the contribution include a full citation to the journal as published by the Medical Research Archives.
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3. Wilson, RT. Directors of Veterinary Services in the Anglo-Egyptian Sudan: setting the scene. Vet Hist, 2018; 19(3): 242-259.
4. Wilson, RT. The one-humped camel in the Anglo-Egyptian military campaigns in Sudan, 1885-1926. J Camel Pact Res, 2016; 23(2): 193-205. doi: 10.5958/2277-8934.2016.00034.5.
5. Abdalatif, YAB., Eisa, MO. and Salih AM. Marketing and export system of camels: a case of Gadaref State Sud J Anim Sci, 2013; 15(1): 1-3.
6. Ahmad, ElGA. A short note on camels export from the Sudan: importers conditions and associated practices. Sud J Sci Tech, 2015; 16(3): 11-14.
7. Mossaad, E., Salim, B., Suganuma, K., Musinguzi, P., Hassan, MA., Elamin, EL., Mohammed, GE., Bakhiet, AO., Xuan, X., Satti, RA. and Inoue N. Trypanosoma vivax is the second leading cause of camel trypanosomosis in Sudan after Trypanosoma evansi. Parasites Vectors, 2017; 10(1): 176. doi: 10.1186/s13071-017-2117-5.
8. Röttcher, D., Schillinger, D. and Zweygarth E. Trypanosomiasis in the camel (Camelus dromedarius). Rev Sci Tech, Off Int Epiz, 1987; 6(2): 463-470.
9. Kula Jilo, Nejash Abdela, Golo Dabasa and Makida Elias. Camel trypanosomiasis: a review on past and recent research in Africa and Middle East. American-Eurasian J Sci Res, 2017; 12(1): 13-20. doi: 10.5829/idosi.aejsr.2017.13.20.
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11. Evans, G. On a horse disease in India known as “surra”, probably due to a hæmatozoon. Vet J and Ann Comp Path, 1881; 13(9): 180-200. https://doi.org/10.1016/S2543-3377(17)43154-2.
12. Hoare, CA. Morphological and taxonomic studies on mammalian trypanosomes. VIII. Revision of Trypanosoma evansi. Parasitology, 1956; 46(1-2): 130-172. doi: 10.1017/S0031182000026408.
13. Fetene, E., Leta, S., Regassa, F. and Büscher. P. Global distribution, host range and prevalence of Trypanosoma vivax: a systematic review and meta-analysis. Parasites Vectors 2021; 14(1): 80. doi: 10.1186/s13071-021-04584-x.
14. El Karib, A. Animal trypanosomiasis in Sudan. Sud J Vet Sci Anim Husb, 1961; 2(1): 39-46.
15. Rahman, AH. 2005. Observations on the trypanosomosis problem outside the tsetse belts of Sudan. Rev Sci Tech, OIE, 2005; 24(3): 965-972.
16. Shommein, AM. and Osman, AM. Diseases of camels in the Sudan. Rev Sci Tech, OIE, 1987; 6(2): 481-486. doi: 10.20506/rst.6.2.298.
17. Parsani, HR., Singh, V. and Momin, RR. Common parasitic diseases of camel. Vet World, 2008; 1(10): 317-318.
18. Woo, PT. The haematocrit centrifuge technique for the diagnosis of African trypanosomiasis. Acta Trop, 1970; 27(4): 384-386.
19. Sadek, AlSM. A comparative study on susceptibility, course of parasitemia, and pattern of infection with Trypanosoma evansi between different laboratory animals. Journal of Taibah University for Science, 2020; 14(1): 1302-1307. doi: 10.1080/16583655.2020.1816323.
20. OIE. OIE-listed diseases, infections and infestations in force in 2021. World Organization for Animal Health, Paris, France. 2021. https://www.oie.int/animal-health-in-the-world/oie-listed-diseases-2021/.
21. Balfour, A. Review of some of the recent advances in tropical medicine: hygiene and tropical veterinary science with special reference to their possible bearing on medical, sanitary and veterinary work in the Anglo-Egyptian Sudan (Third report of the Wellcome Research Laboratories at the Gordon Memorial College, Khartoum). Department of Education, Sudan Government, Khartoum, Sudan. 1908.
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