Plastic Chemical Bisphenol A Dampens Our Cardiovascular System: Evidence from Clinical and Animal Studies

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Saif Khan Shinyi Ding Aimee Hong Abel Ketama Jiwang Chen


The environmental exposure of Bisphenol A (BPA) is a pervasive and growing concern. BPA is a high-volume industrial chemical that possesses estrogen-like properties and functions as an environmental endocrine disruptor. It is used extensively in the production of polycarbonate plastics and epoxy resins for food and beverage packages and hygienic products. An increasing amount of plastic pollution prevalent throughout the world has resulted in the nearly ubiquitous exposure of BPA towards humans and animals alike. Concerns have surfaced accordingly, surrounding the potentially detrimental effects that might result from BPA leaching into foods and beverages. The increase in epidemiological studies related to BPA have since been able to conclude links between BPA-induced oxidative stress, cardiovascular diseases, and hypertension. This review will incorporate current literature examining BPA exposure through clinical and epidemiological trials; these trials will encompass the physiological and toxicological effects that BPA can impose on the human cardiovascular system.

Keywords: bisphenol A, cardiovascular disease, hypertension, clinical studies, preclinical studies, mechanism

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How to Cite
KHAN, Saif et al. Plastic Chemical Bisphenol A Dampens Our Cardiovascular System: Evidence from Clinical and Animal Studies. Medical Research Archives, [S.l.], v. 9, n. 11, nov. 2021. ISSN 2375-1924. Available at: <>. Date accessed: 29 may 2023. doi:
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