Re-treatment of Prostate Cancer with Radiation Therapy
Main Article Content
Abstract
As treatment for prostate cancer matures with many options for local, regional and systemic care, patients are living longer. Coupled with aggressive therapy for oligometastatic disease and improvements in multiple treatment pathways including radiopharmacy, both disease-free and overall survival are improving for many patients. Success can also bring new challenges that require new thought processes for care. In this paper we present two patients who had undergone previous radiation therapy for adenocarcinoma of the prostate with curative intent who required consideration for re-irradiation each more than 15 years away from primary management.
Article Details
The Medical Research Archives grants authors the right to publish and reproduce the unrevised contribution in whole or in part at any time and in any form for any scholarly non-commercial purpose with the condition that all publications of the contribution include a full citation to the journal as published by the Medical Research Archives.
References
2. Pasquier D, Martinage G, Janoray G, et al. Salvage stereotactic body radiation therapy for local prostate cancer recurrence after radiation therapy: A retrospective multicenter study of the GETUG. Int J Radiat Oncol Biol Phy.s 2019;105:727-734.
3. Fuller DB, Wurzer J, Shirazi R, Bridge SS, Law J, Mardirossian G. High-dose-rate stereotactic body radiation therapy for postradiation therapy locally recurrent prostatic carcinoma: Preliminary prostate-specific antigen response, disease-free survival, and toxicity assessment. Pract Radiat Oncol. 2015;5:e615-e623.
4. Mbeutcha A, Chauveinc L, Bondiau PY, et al. Salvage prostate re-irradiation using high-dose-rate brachytherapy or focal stereotactic body radiotherapy for local recurrence after definitive radiation therapy. Radiat Oncol. 2017;12:49.
5. Créhange G, Roach M III, Martin E, et al. Salvage reirradiation for local regional failure after radiation therapy for prostate cancer: who, when, where and how? Cancer Radiother. 2014;18:524-534.
6. Baty M, Créhange G, Pasquier D, et al. Salvage reirradiation for local prostate cancer recurrence after radiation therapy. For who? When? How? Cancer Radiother . 2019;23:541-558.
7. Taillez A, Bimbai AM, Lacornerie T, Le Deley MC, Lartigau EF, Pasquier D. Studies of intrafraction motion prostate motion during stereotactic irradiation in first irradiation and re-irradiation. Front Oncol. 2021;11:690422.
8. Lewin R, Amit U, Laufer M, et al. Salvage re-irradiation using stereotactic body radiation therapy for locally recurrent prostate cancer: the impact of castration sensitivity on treatment outcomes. Radiat Oncol. 2021; 16: 114.
9. Cuccia F, Corradini S, Mazzola R, et al. MR-guided hypofractionated radiotherapy: Current emerging data and promising perspectives for localized prostate cancer. Cancers (Basel). 2021; 13: 1791.
10. Cuccia F, Nicosia L, Mazzola R, et al. Linac-based SBRT as a feasible salvage option for local recurrences in previously irradiated prostate cancer. Strahlenther Onkol. 2020;196:628-636.
11. Mohler JL, Halabi S, Ryan ST, et al. Management of recurrent prostate cancer after radiotherapy: long-term results from CALGB 9687 (Alliance), a prospective multi-institutional salvage prostatectomy series. Prostate Cancer Prostatic Dis. 2019;22(2):309-316.