Abstract
Since the outbreak of the COVID-19 pandemic, there have been myriad signs and symptoms ascribed to this disease process. While some of the most notable features described since the initial months of the pandemic include cough, fever, myalgia, headache, dyspnea/hypoxia, anosmia, and multifocal pneumonia, the pandemic’s prolonged continuation has afforded ample opportunity to detect more subtle signs of the disease. Mediastinal adenopathy is one such sign that has been found in many patients with active COVID-19 infection, though the value of this finding in both prognostication and guiding treatment remains unknown. We did a timely brief review of mediastinal adenopathy in COVID-19 infection to shed more light on the potential implications of this finding. We conclude that Mediastinal Adenopathy in hospitalized COVID-19 patients has been associated with higher ICU admissions and higher mortality. Its non-specific nature and confounding etiology may prevent it from being a good marker for prognosticator of COVID-19 disease severity.