Dietary Treatments to Reduce Insulin Resistance and Inflammation in Type-2 Diabetic Patients
Main Article Content
Abstract
Type 2 diabetes (T2D) has increased dramatically in the last 20 years afflicting more than 425 million people all over the world with 34 million located in the US, emphasizing the need for strategic therapies including dietary prescriptions or other lifestyle changes to reduce these numbers. In addition to abnormally high plasma glucose levels, high concentrations of glycosylated hemoglobin and insulin resistance, T2D is also characterized by dyslipidemias, oxidative stress, and low-grade systemic inflammation. Insulin resistance and inflammation in T2D can lead to cardiac problems, non-alcoholic fatty liver disease and kidney failure. T2D can be controlled by modifying current unhealthy practices by focusing on wholesome diets, exercise regimes and maintenance of a healthy body weight. In this review, we aim to demonstrate how specific dietary prescriptions including carbohydrate restriction, the Mediterranean diet, plant-based diets and the dietary approaches to treat hypertension (DASH) can improve not just the inflammatory response and reduce the biomarkers of inflammation but also have additional benefits on insulin resistance, weight loss, plasma lipids and blood pressure. In addition, the mechanistic evaluation of specific nutrients including antioxidants (polyphenols and carotenoids), certain fatty acids and vitamins and their exclusive role in decreasing inflammation will be discussed.
Keywords:
type 2 diabetes, inflammation, insulin resistance, dyslipidemia, dietary treatments, antioxidants
Article Details
How to Cite
FERNANDEZ, Maria Luz; MURILLO, Ana Gabriela.
Dietary Treatments to Reduce Insulin Resistance and Inflammation in Type-2 Diabetic Patients.
Medical Research Archives, [S.l.], v. 10, n. 4, apr. 2022.
ISSN 2375-1924.
Available at: <https://esmed.org/MRA/mra/article/view/2768>. Date accessed: 21 nov. 2024.
doi: https://doi.org/10.18103/mra.v10i4.2768.
Section
Research Articles
The Medical Research Archives grants authors the right to publish and reproduce the unrevised contribution in whole or in part at any time and in any form for any scholarly non-commercial purpose with the condition that all publications of the contribution include a full citation to the journal as published by the Medical Research Archives.
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