Case Report: COVID-19 With Spontaneous Pneumothorax, Pneumomediastinum and Subcutaneous Emphysema

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Martínez-Hernández martínez Lucia Choi Su Jung Medina-García Gerardo Lorenzo-Silva José Manuel López-Enríquez Claudia Donís-Hernández José


To date, few report cases of spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema without any cause of trauma have been observed in patients with COVID-19 pneumonia. We present a case of a 66-year-old male patient who developed such complication on day 19 of hospitalization, without requiring non-invasive or invasive ventilator. CT thorax scan revealed widespread bilateral ground glass opacities with pneumothorax, pneumomediastinum, and subcutaneous emphysema, which were resolved totally on the following 29 days. We highlight preexisting mechanisms for pulmonary air-leak syndrome and importance of prompt recognition to establish adequate therapy in patients with COVID-19 pneumonia.


Keywords: COVID-19, 2019-nCoV, pneumonia, SARS-CoV-2, pneumothorax, pneumomediastinum, subcutaneous emphysema

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LUCIA, Martínez-Hernández martínez et al. Case Report: COVID-19 With Spontaneous Pneumothorax, Pneumomediastinum and Subcutaneous Emphysema. Medical Research Archives, [S.l.], v. 10, n. 7, july 2022. ISSN 2375-1924. Available at: <>. Date accessed: 30 may 2023. doi:
Case Reports


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