Severe Neurological Manifestations of Multisystem Inflammatory Syndrome in Adults (MIS-A)

Main Article Content

Boby Varkey Maramattom, MD,DM, FRCP, FRCPE, FICCN

Abstract

Introduction; Multi-system inflammatory syndrome (MIS) is a para infectious or post infectious extra-pulmonary complication of COVID-19. Neurological complications are better described in children with multi-system inflammatory syndrome (MIS) in children (MIS-C). There is a paucity of literature about severe neurological manifestations of multi-system inflammatory syndrome in adults (MIS-A).


Methods; Over a 22-month period, from June 2020 to December 2021, over 3450 COVID patients were admitted to our institution including 900 patients in the medical and COVID ICUs. Ten patients (1.1%) presented to us with MIS-A with severe neurological manifestations.


Results; Severe neurological manifestations included transverse myelitis, COVID encephalitis, acute encephalopathy, status epilepticus and rhabdomyolytic myopathy. Our cohort had a high morbidity and mortality rate.


Conclusions; Most patients with MIS-A had severe neurological involvement and a poor outcome.

Article Details

How to Cite
MARAMATTOM, Boby Varkey. Severe Neurological Manifestations of Multisystem Inflammatory Syndrome in Adults (MIS-A). Medical Research Archives, [S.l.], v. 10, n. 7, july 2022. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/2908>. Date accessed: 08 aug. 2022. doi: https://doi.org/10.18103/mra.v10i7.2908.
Section
Research Articles

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