Study of Outcome After One Year Follow Up of Tuberculosis Patients After the Completion of Treatment in Tertiary Care Center in Western Maharashtra

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Kiran Kumar Kompella, Dr Someshwar Gaikwad, Dr Anuj Singhal, Prof Vishal Mangal, Dr Arun Kumar Yadav, Dr Saurav Kumar Chauhan, Dr

Abstract

Background: Tuberculosis (TB) still remains an important public health problem in India. After completion of treatment, we hardly know that what happened to these cases once they are declared as cured and released in community. Hence the study was conducted to find out the outcomes and factors associated with them.


Material and methods: It was a longitudinal observational study. Patients were followed up for up to one year after completion of the treatment for weight gain, and adverse side effects.


Results: In our study 91 % of the cases were cured, 1.7 % were treatment failure and 2.18 % died. All the cases of recurrent TB were cured. HIV and TB co-infection was found in 15.7 % cases. 85% of patients tolerated the anti-tubercular therapy (ATT) well. The incidence of extra pulmonary TB was 19.2 %. Out of 229 cases 16 failed to gain weight at the end of therapy. The gain in weight was statistically significant (p value <0.001). The adverse outcome was seen in 20 cases.


Conclusion: In our study, 91 % of the cases including 100% of recurrent Tb cases were cured because of newer RNTCP program. The incidence of extra pulmonary TB was higher than the national average. The majority (85%) of patients tolerated the anti-tubercular therapy (ATT) well. Out of 229 cases, only 16 patients failed to gain weight at the end of therapy. The gain in weight was significant predictor of good outcome in treating tuberculosis. The factors like weight gain, age, sex, place of stay or comorbidities were not associated as predictors of poor outcome. However, presence of co-morbidity like HIV and Diabetes may be associated with poor outcome but a higher sample size may be required to confirm it.


Key Message: This study highlighted the importance of weight gain after IP in tuberculosis patients on ATT. The extra pulmonary TB is far more common than national average.

Keywords: Tuberculosis, weight gain, HIV-TB coinfection, predictors of outcome

Article Details

How to Cite
KOMPELLA, Kiran Kumar et al. Study of Outcome After One Year Follow Up of Tuberculosis Patients After the Completion of Treatment in Tertiary Care Center in Western Maharashtra. Medical Research Archives, [S.l.], v. 10, n. 8, aug. 2022. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/3004>. Date accessed: 18 apr. 2024. doi: https://doi.org/10.18103/mra.v10i8.3004.
Section
Case Reports

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