Neuroscience as the New Approach to Treating Obesity

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Franchell Richard Hamilton

Abstract

Obesity continues to be on the rise despite all of its advances in medications and surgeries, not to mention the invasiveness of the diet and fitness industry in this area. More than 72% of the U.S population is overweight or obese, and obesity is now rising in the pediatric population affecting our next generation. (1) Obesity on its own occupies a large part of health expenditures in the globe and has been the catalyst for over 200 other diseases identified. This chronic relapsing disease over time has been one of the most invasive to our nation and the most difficult to treat.


We have seen relapse rates from diet and medication over 90% and post bariatric surgery recurrence rates long  term have been more than 70%. (3) The World Health Organization states that 2.8 million people die of obesity each year, a preventable disease. (4) Even when the name was changed several years ago by  the American College of Endocrinology the epidemic continued to rise. At what point will the overseeing bodies decide that this is no longer good enough? As a bariatric surgeon, also board certified in obesity medicine, I am familiar with all the treatment algorithms for obesity and have practiced those for years. After seeing surgeries require 2 and 3 revisions due to weight recurrence I had to ask what was missing in the algorithm? After years of watching my patients struggle they answered that question for me. The addition of neurobehavioral science is what was missing.

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How to Cite
HAMILTON, Franchell Richard. Neuroscience as the New Approach to Treating Obesity. Medical Research Archives, [S.l.], v. 10, n. 10, oct. 2022. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/3242>. Date accessed: 28 nov. 2022. doi: https://doi.org/10.18103/mra.v10i10.3242.
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Letters to Editor

References

1) Flegal, K. M., Kruszon-Moran, D., Carroll, M. D., Fryar, C. D., & Ogden, C. L. (2016). Trends in Obesity Among Adults in the United States, 2005 to 2014. JAMA, 315(21), 2284–2291. https://doi.org/10.1001/jama.2016.6458
2) De Lorenzo, A., Gratteri, S., Gualtieri, P., Cammarano, A., Bertucci, P., & Di Renzo, L. (2019). Why is primary obesity a disease?. Journal of translational medicine, 17(1), 169. https://doi.org/10.1186/s12967-019-1919-y
3) Velapati, S.R., Shah, M., Kuchkuntla, A.R. et al. Weight Regain After Bariatric Surgery: Prevalence, Etiology, and Treatment. Curr Nutr Rep 7, 329–334 (2018). https://doi.org/10.1007/s13668-018-0243-0
4) https://www.who.int/news-room/facts-in-pictures/detail/6-facts-on-obesity
5) Mallan KM, Sullivan SE, Susan J, Daniels LA. The relationship be- tween maternal feeding beliefs and practices and perceptions of infant eating behaviors at 4 months. Appetite. 2016;105:1–7.
6) Antonio Alcaro, Robert Huber, and Jaak Panksepp. Behavior functions of the mesolimbic Dopaminergic system. An Affective Neuroethological Perspective. Brain Res Rev. 2007 Dec; 56(2): 283–321. 10.1016/j.brainresrev.2007.07.014
7) Wise RA, Bozarth MA. A psychomotor stimulant theory of addiction. Psychol Rev. 1987;94(4):469–92.
8) Neal, D., Nathan G., (2013) Habits not cravings drive food choices. Institute of Food technologies, ScienceDaily. 16July
9) Busetto, L., Bettini, S., Makaronidis, J., Roberts, C. A., Halford, J., & Batterham, R. L. (2021). Mechanisms of weight regain. European journal of internal medicine, 93, 3–7.
10) Shintaro Funahashi, Prefrontal Contribution to Decision-Making under Free-Choice Conditions. Front. Neurosci., 26 July 2017. https://doi.org/10.3389/fnins.2017.00431
11) Rodrigo Sosa, Jesús Mata-Luévanos and Mario Buenrostro-Jáuregui. The role of the lateral Habenula in inhibitory learning from reward Omission. eNeuro 7 May 2021, 8 (3) ENEURO.0016-21.2021. https://doi.org/10.1523/ENEURO.0016-21.2021