Covid-19 In Children: A Single Centered Study

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Rajendra Nerli Sonali Bijjargi Shridhar C. Ghagane Swapnil A. Pattanshetti Shadab Rangrez Shreyas Rai

Abstract

Introduction: There is limited data available on the epidemiological features, clinical manifestations, and transmission patterns in children with COVID-19, although there has been widespread information available regarding COVID-19 in adults. The objective of our study was to report our experience in the management of children admitted with COVID-19 to our hospital.


Materials & Methods: We retrospectively reviewed the in-patient records of all children  18 years of age admitted to our COVID-19 facility during the period March 2020 till May 2021. Detailed information including demographic data, travel and contact history, living conditions and overcrowding, symptoms, and presence of co-morbid conditions were noted. The clinical symptoms, physical findings, laboratory readings and imaging data were similarly noted and analysed.


Results: During the study period a total of 67 children (30 males and 37 females) with a mean age of 11.88 4.35 years were admitted to the COVID-19 facility. The presenting symptoms were fever (71.64%), skin rashes (14.93%), breathlessness (7.46%), cough (31.34%), cold (2.99%), headache (8.96%), sore throat (25.37%), loose motions (26.87%) and vomiting (8.96%). The RT-PCR was positive in 60 (89.55%) children. Sixty-one (91.045%) children recovered over a period of 10-14 days and were discharged.  Six (8.955%) children died due to multisystem failure. When compared to the children who recovered, the children who died had a significantly raised serum ferritin, IL 6, C reactive proteins, D-Dimer levels, and Sr LDH.


Conclusions: COVID-19 has been affecting children, more so in the second wave, with increased hospitalizations and mortality.

Keywords: COVID-19, Children, hospitalizations, mortality

Article Details

How to Cite
NERLI, Rajendra et al. Covid-19 In Children: A Single Centered Study. Medical Research Archives, [S.l.], v. 11, n. 1, jan. 2023. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/3337>. Date accessed: 20 may 2024. doi: https://doi.org/10.18103/mra.v11i1.3337.
Section
Research Articles

References

1. Narasimhan TE. India's first coronavirus case: Kerala student in Wuhan tested positive. Business Standard News. https://www.business-standard.com/article/current-affairs/india-s-first-coronavirus-case-kerala-student-in-wuhan-tested-positive-120013001782_1.html. Published January 31, 2020. Accessed January 21, 2023.
2. #Indiafightscorona Covid-19 - MyGov.in. https://www.mygov.in/covid-19/. Accessed January 21, 2023.
3. Al Jazeera. India's Covid Crisis 'beyond heartbreaking': Who. Coronavirus pandemic News | Al Jazeera. https://www.aljazeera.com/news/2021/4/26/india-sets-new-covid-world-record-for-5th-straight-day-live-news. Published November 9, 2021. Accessed January 21, 2023.
4. Sarangi B, Reddy VS, Oswal JS, et al. Epidemiological and clinical characteristics of COVID-19 in Indian children in the initial phase of the pandemic. Indian Pediatrics. 2020;57(10):914-917. doi:10.1007/s13312-020-1994-4.
5. Sarangi B, Reddy VS, Oswal JS, et al. Epidemiological and clinical characteristics of COVID-19 in Indian children in the initial phase of the pandemic. Indian Pediatrics. 2020;57(10):914-917. doi:10.1007/s13312-020-1994-4
6. Donnelly CA, Ghani AC, Leung GM, et al. Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong. The Lancet. 2003;361(9371):1761-1766. doi:10.1016/s0140-6736(03)13410-1
7. Cauchemez S, Fraser C, Van Kerkhove MD, et al. Middle East respiratory syndrome coronavirus: Quantification of the extent of the epidemic, surveillance biases, and transmissibility. The Lancet Infectious Diseases. 2014;14(1):50-56. doi:10.1016/s1473-3099(13)70304-9
8. Coronavirus disease (covid-19) situation reports. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports. Accessed January 21, 2023.
9. The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team None; The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) - china, 2020. China CDC weekly. https://pubmed.ncbi.nlm.nih.gov/34594836/. Accessed January 21, 2023.
10. Qiu H, Wu J, Hong L, Luo Y, Song Q, Chen D. Clinical and epidemiological features of 36 children with coronavirus disease 2019 (covid-19) in Zhejiang, China: An observational cohort study. The Lancet Infectious Diseases. 2020;20(6):689-696. doi:10.1016/s1473-3099(20)30198-5
11. Meena J, Yadav J, Saini L, Yadav A, Kumar J. Clinical features and outcome of SARS-COV-2 infection in children: A systematic review and meta-analysis. Indian Pediatrics. 2020;57(9):820-826. doi:10.1007/s13312-020-1961-0
12. Coronavirus disease 2019 in children - United States, February 12-April 2, 2020. MMWR. Morbidity and mortality weekly report. https://pubmed.ncbi.nlm.nih.gov/32271728/. Accessed January 21, 2023.
13. Chen Y, Peng H, Wang L, et al. Infants born to mothers with a new coronavirus (COVID-19). Frontiers in Pediatrics. 2020;8. doi:10.3389/fped.2020.00104
14. Patel NA. Pediatric covid-19: Systematic review of the literature. American Journal of Otolaryngology. 2020;41(5):102573. doi:10.1016/j.amjoto.2020.102573
15. Jain S, Sen S, Lakshmivenkateshiah S, et al. Multisystem inflammatory syndrome in children with covid-19 in Mumbai, India. Indian Pediatrics. 2020;57(11):1015-1019. doi:10.1007/s13312-020-2026-0.
16. Nerli R, Sanikop A, Sharma M, Ghagane S. Covid-19 pandemic: A Challenge to a child with cancer. 2020. doi:10.22541/au.159076935.53810399