Corrosive Ingestion in Children: Clinical, Laboratory and Endoscopic Findings

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Published Nov 10, 2023
DOI: https://doi.org/10.18103/mra.v11i10.3494

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Main Article Content

Sinem Oral Cebeci, M.D.
Department of Pediatrics, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey
Hasret Ayyıldız Civan, M.D.
Department of Gastroenterology, Hepatology and Nutrition; Bakırköy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey

Abstract

Background and aim: Caustic substance ingestion usually occurs accidental in children or voluntary in suicidal adolescents. The tissue damage depends on type of corrosive chemicals, location of injury, duration, and amount. Endoscopy still remains as a reliable and gold standard procedure to evaluate the tissue injury. Thus, we aimed to compare the clinical, laboratory and gastroscopic findings of children presented with corrosive substance ingestion in relation with the ingested corrosive substance type in our study.


Material and Method: One hundred forty-one children and adolescents (62 female, 79 male) presented with caustic substance ingestion history within 24 hours, were evaluated retrospectively. Patients' demographic characteristics, ingested type and form (acid or base) of corrosive chemicals, gastroscopic findings, laboratory results were recorded and compared.


Results: The mean age was significantly higher in female patients (3,60±3,81) than male patients (2,27±2,89) (p=0,000). Caustic substance ingestion prevalence (69.5%) was peaked in the 0-3 age group. Of the patients 84,4% presented with no symptom. Bleacher was the most common corrosive substance (31.9%), followed by rinse aid (16.3%) and other substances (14.9%). 65,2% of caustic substance ingestions were caused by alkaline substances, and 18,4% by acidic agents. According to the gastroscopy findings underlying pathology was detected in 31,9% (n=45) of the cases. The stage I corrosive esophagitis was the most common pathology with a rate of %51,1. There were no statistically significant differences found according to the ingested form of corrosive agents [acid (34,6%) vs. base (27,2%)] between the patients with negative and positive baseline gastroscopy findings. But the mean value of neutrophile/lymphocyte ratio was statistically higher in the cases with ingested alkaline corrosive agents (0,96±0,80) than patients with ingested acidic corrosive agents (0,85±1,06) (p=0,016).


Conclusions: The findings of the present study suggest that elevated the neutrophil-lymphocyte ratio would improve diagnostic accuracy in cases with caustic substance ingestion. Therefore, widely available, simple, minimally invasive, and cost-effective hematological parameters suggest potential clinical benefits in cases with caustic injury. Furthermore, since ingestion of caustic agents is simply preventable issue in children, appropriate public education programs should provide by governments.


 

Keywords: Corrosive ingestion, Caustic injury, Corrosive agents, Pediatric Gastroscopy, Pediatric emergency

Article Details

How to Cite
CEBECI, Sinem Oral; CIVAN, Hasret Ayyıldız. Corrosive Ingestion in Children: Clinical, Laboratory and Endoscopic Findings. Medical Research Archives, [S.l.], v. 11, n. 10, nov. 2023. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/3494>. Date accessed: 23 nov. 2024. doi: https://doi.org/10.18103/mra.v11i10.3494.
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Issue
Vol 11 No 10 (2023): October Issue, Vol.11, Issue 10
Section
Research Articles

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