Acromegalic Arthropathy and Ossification of the Yellow Ligament Treated with an Interlaminar Full-Endoscopic Approach: A Case Report Full-endoscopic decompression in a patient with acromegaly and Ossification of the Posterior Longitudinal Ligament

Main Article Content

Pedro Luz Alves Estela Alves De Oliveira David Del Curto Renato Hiroshi Salvioni Ueta Eduardo Barros Puertas

Abstract

Introduction: Acromegalic arthropathy is a cause of morbidity and functional disability, affecting large peripheral joint, especially the spine. Affected patients can suffer from lumbar and sciatic pain, with or without radiculopathy. Due to the severe arthrosis, stenosis with ossification of the ligamentum flavum can often occur.


Patient history: This study presents a 57-year-old patient with acromegalic arthropathy resulting from a growth hormone secreting pituitary macroadenoma. He was previously submitted to transsphenoidal surgery and present a history of L4-L5 decompression due to disc herniation and bilateral knee arthroplasty. The condition evolved to an acute left lumbar sciatic pain and the patient was refractory to clinical and physical therapy treatment. Surgical procedure: Decompression and discectomy were performed through an interlaminar endoscopic approach. Cutting and diamond burs and Keirrinson-type forceps were used for decompression. Diamond burs were used in the calcified yellow ligament and in the intervertebral disc to remove the protruding disc.Imaging exams: Preoperative exams showed calcified disc herniation and stenosis, with ossification of the posterior longitudinal ligament. Postoperative exams showed good decompression, removal of the calcified disc herniation and ossification of the posterior longitudinal ligament.Patient follow-up: Immediate resolution of sciatica pain and neurological deficit, with a negative nerve stretching test. At one-year follow-up, the patient had no return of radicular symptoms.Conclusion: Endoscopic surgery can be a reliable treatment option in approaching patients with severe stenosis of the spinal canal associated with calcified disc hernias and ossification of the ligamentum flavum, even when submitted to previous surgeries. This approach also presents benefits of a minimally invasive surgery.

Keywords: Acromegaly, Arthropathy, Ossification of the ligamentum flavum, calcified disc herniation, Full-endoscopic spine surgery, minimally invasive, Radiculopathy

Article Details

How to Cite
ALVES, Pedro Luz et al. Acromegalic Arthropathy and Ossification of the Yellow Ligament Treated with an Interlaminar Full-Endoscopic Approach: A Case Report. Medical Research Archives, [S.l.], v. 11, n. 7.2, july 2023. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/4027>. Date accessed: 23 nov. 2024. doi: https://doi.org/10.18103/mra.v11i7.2.4027.
Section
Case Reports

References

1. Claessen KM, Mazziotti G, Biermasz NR, Giustina A. Bone and Joint Disorders in Acromegaly. Neuroendocrinology. 2016;103:86-95. doi:10.1159/000375450
2. Colao A, Pivonello R, Scarpa R, Vallone G, Ruosi C, Lombardi G. The acromegalic arthropathy. J Endocrinol Invest. 2005;28:24-31.
3. Donangelo I, Une K, Gadelha M. Diagnosis and treatment of acromegaly in Brazil. Arq Bras Endocrinol Metab. 2003;47:331-346. doi:10.1590/S0004-27302003000400006
4. Cirolia JT. Acromegalic Arthropathy. J Orthop Sports Phys Ther. 2019;49:864. doi:10.2519/jospt.2019.8302
5. Perpignano G, Cacace E, Beccaris A, et al. Acromegalic arthropathy. Clin Ter. 1993;143:3-9.
6. Raja A, Hoang S, Patel P, Mesfin FB. Spinal Stenosis. StatPearls Publishing. Updated July 17, 2022. Accessed May 29, 2023. https://www.ncbi.nlm.nih.gov/books/NBK441989/
7. Chen Y, Wang JX, Sun B, et al. Percutaneous Endoscopic Lumbar Discectomy in Treating Calcified Lumbar Intervertebral Disc Herniation. World Neurosurg. 2019;122:e1449-e1456. doi:10.1016/j.wneu.2018.11.083
8. Shin SH, Bae JS, Lee SH, Keum HJ, Kim HJ, Jang WS. Transforaminal Endoscopic Decompression for Lumbar Spinal Stenosis: A Novel Surgical Technique and Clinical Outcomes. World Neurosurg. 2018;114:e873-e882. doi:10.1016/j.wneu.2018.03.107
9. Kim HS, Adsul N, Ju YS, et al. Full Endoscopic Lumbar Discectomy using the Calcification Floating Technique for Symptomatic Partially Calcified Lumbar Herniated Nucleus Pulposus. World Neurosurg. 2018;119:500-505. doi:10.1016/j.wneu.2018.06.133
10. Dabo X, Ziqiang C, Yinchuan Z, et al. The Clinical Results of Percutaneous Endoscopic Interlaminar Discectomy (PEID) in the Treatment of Calcified Lumbar Disc Herniation: A Case-Control Study. Pain Physician. 2016;19:69-76.
11. Ruetten S, Komp M, Merk H, Godolias G. Use of newly developed instruments and endoscopes: full-endoscopic resection of lumbar disc herniations via the interlaminar and lateral transforaminal approach. J Neurosurg Spine. 2007;6:521-30. doi:10.3171/spi.2007.6.6.2
12. Bengtsson BA, Eden S, Ernest I, Oden A, Sjogren B. Epidemiology and long-term survival in acromegaly. A study of 166 cases diagnosed between 1955 and 1984. Acta Med Scand. 1988;223:327-35. doi:10.1111/j.0954-6820.1988.tb15881.x
13. Polgar F. Über interarkuelle wirbelverkalkung. Fortschr Geb Rontgenst r Nuklearmed Erganzungsband. 1920;40:292-298.
14. Yano T, Doita M, Iguchi T, et al. Radiculopathy due to ossification of the yellow ligament at the lower lumbar spine. Spine (Phila Pa 1976). 2003;28:E401-4. doi:10.1097/01.BRS.0000092347.32845.43
15. Yoshida M, Shima K, Taniguchi Y, Tamaki T, Tanaka T. Hypertrophied ligamentum flavum in lumbar spinal canal stenosis. Pathogenesis and morphologic and immunohistochemical observation. Spine (Phila Pa 1976). 1992;17:1353-60. doi:10.1097/00007632-199211000-00015
16. Szpalski M, Gunzburg R. Lumbar spinal stenosis in the elderly: an overview. Eur Spine J. 2003;12 Suppl 2:S170-5. doi:10.1007/s00586-003-0612-1
17. Yamada T, Shindo S, Yoshii T, et al. Surgical outcomes of the thoracic ossification of ligamentum flavum: a retrospective analysis of 61 cases. BMC Musculoskelet Disord. 2021;22:7. doi:10.1186/s12891-020-03905-y
18. Daniels AH, McDonald CL, Basques BA, Kuris EO. Ossified Ligamentum Flavum: Epidemiology, Treatment, and Outcomes. J Am Acad Orthop Surg. 2022;30:e842-e851. doi:10.5435/JAAOS-D-21-01253
19. Iwai H, Inanami H, Koga H. Full-Endoscopic Spine Surgery for the Treatment of Lumbar Ossification of the Ligamentum Flavum: Technical Report. World Neurosurg. 2020;142:487-494 e1. doi:10.1016/j.wneu.2020.06.132
20. Yoshida M, Tamaki T. Pathology of ossification of the ligamentum flavum. In: Yonenobu K, Sakou T, Ono K, eds. OPLL: Ossification of the Posterior Longitudinal Ligament. Springer; 1997:49-58.
21. Gerlach R, Zimmermann M, Kellermann S, Lietz R, Raabe A, Seifert V. Intervertebral disc calcification in childhood--a case report and review of the literature. Acta Neurochir (Wien). 2001;143:89-93. doi:10.1007/s007010170143
22. Suwa H, Hanakita J, Ohshita N, Gotoh K, Matsuoka N, Morizane A. Postoperative changes in paraspinal muscle thickness after various lumbar back surgery procedures. Neurol Med Chir (Tokyo). 2000;40:151-4; discussion 154-5. doi:10.2176/nmc.40.151
23. Deyo RA, Mirza SK, Martin BI, Kreuter W, Goodman DC, Jarvik JG. Trends, major medical complications, and charges associated with surgery for lumbar spinal stenosis in older adults. JAMA. 2010;303:1259-65. doi:10.1001/jama.2010.338
24. Rasouli MR, Rahimi-Movaghar V, Shokraneh F, Moradi-Lakeh M, Chou R. Minimally invasive discectomy versus microdiscectomy/open discectomy for symptomatic lumbar disc herniation. Cochrane Database Syst Rev. 2014:CD010328. doi:10.1002/14651858.CD010328.pub2
25. Ahn Y. Endoscopic spine discectomy: indications and outcomes. Int Orthop. 2019;43:909-916. doi:10.1007/s00264-018-04283-w
26. Jarebi M, Awaf A, Lefranc M, Peltier J. A matched comparison of outcomes between percutaneous endoscopic lumbar discectomy and open lumbar microdiscectomy for the treatment of lumbar disc herniation: a 2-year retrospective cohort study. Spine J. 2021;21:114-121. doi:10.1016/j.spinee.2020.07.005
27. Kotheeranurak V, Liawrungrueang W, Quillo-Olvera J, et al. Full-Endoscopic Lumbar Discectomy Approach Selection: A Systematic Review and Proposed Algorithm. Spine (Phila Pa 1976). 2023;48:534-544. doi:10.1097/BRS.0000000000004589
28. Cheng YP, Cheng XK, Wu H. A comparative study of percutaneous endoscopic interlaminar discectomy and transforaminal discectomy for L5-S1 calcified lumbar disc herniation. BMC Musculoskelet Disord. 2022;23:244. doi:10.1186/s12891-022-05186-z
29. Gao A, Yang H, Zhu L, et al. Comparison of Interlaminar and Transforaminal Approaches for Treatment of L(5) /S(1) Disc Herniation by Percutaneous Endoscopic Discectomy. Orthop Surg. 2021;13:63-70. doi:10.1111/os.12831
30. Ahn Y, Oh HK, Kim H, Lee SH, Lee HN. Percutaneous endoscopic lumbar foraminotomy: an advanced surgical technique and clinical outcomes. Neurosurgery. 2014;75:124-33; discussion 132-3. doi:10.1227/NEU.0000000000000361