The Role of Nutritional Modulation of Immune Function in Cancer – What About It?

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Published Jun 26, 2023
DOI: https://doi.org/10.18103/mra.v11i6.4038

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Main Article Content

João Vasco Barreira
Oncology Department, CUF Oncologia, Portugal. ; Universidade Católica Portuguesa - Institute of Health Sciences, Portugal. ;  AIM Cancer Center, Portugal.
Pedro Barreira
AIM Cancer Center, Portugal. ; General and Family Medicine Department, CUF Belém & Miraflores Clinic, Portugal.
Mariana Amaral
General and Family Medicine Department, USF Fonte Luminosa, Portugal.
José Leão Mendes
Oncology Department, Centro Hospitalar Universitário Lisboa Central, Portugal.
Catarina Ribeiro
AIM Cancer Center, Portugal

Abstract

In recent years there has been an increase in the number of new cases of cancer. Malnutrition in cancer patients is a consequence of the increase in inflammatory cytokines associated with cancer, metabolic alterations, and concomitant inadequate availability of nutrients, due to anorexia caused by the disease and systemic treatments. Nutrition can guide both the growth and progress of inflammatory disorders and their prevention and treatment. Irrevocably, it is indispensable to pair the diet with physical activity, balance nutritional status and prime a healthy lifestyle. An increased understanding of the instruments linked to nutrients and the immune system is a breathtaking and exceptional field for the future. The gut microbiota is now known as a fundamental factor disturbing the host´s anti-cancer immunosurveillance and capacity to respond to immunotherapy. Diet is one of the most powerful modulators of microbiota, and therefore nutritional intervention could be used to increase host anti-cancer immunity. A rising body of data has also highlighted that the gut microbiota may have a constructive impact on cancer prevention or treatment, particularly via improved host immunosurveillance of cancer as well as patients ‘capacity to respond to chemotherapy or immunotherapy. The sway of nutrition on the immune system is a territory that remains under investigation. Nutrition and immunity are closely related. An expanded understanding of the mechanisms connected to nutrients and the immune system is a breathtaking and gifted field for the future.

Article Details

How to Cite
BARREIRA, João Vasco et al. The Role of Nutritional Modulation of Immune Function in Cancer – What About It?. Medical Research Archives, [S.l.], v. 11, n. 6, june 2023. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/4038>. Date accessed: 15 may 2024. doi: https://doi.org/10.18103/mra.v11i6.4038.
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Issue
Vol 11 No 6 (2023): June Issue, Vol.11, Issue 6
Section
Research Articles

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