Myocardial lesions during Severe Acute Respiratory Syndrome Coronavirus 2 infection
Main Article Content
Abstract
The Severe Acute Respiratory Syndrome Coronavirus 2 virus has a strong tropism for the cardiovascular system, with direct or indirect interactions mediated by inflammation. The virus can cause cardiovascular lesions that can compromise the prognosis. We report the case of a 43-year-old patient with no particular medical history, admitted with acute respiratory distress syndrome due to coronavirus disease 2019 pneumonia complicated by myocardial injury, whose condition gradually improved with apyrexia, normalization of troponins, inflammatory markers, and restoration of left ventricular function. This case report demonstrates the need to identify cardiac involvement through widespread use of echocardiography and close monitoring of cardiac and inflammatory biomarkers during coronavirus disease 2019 infection, given the prognostic implications of such involvement.
Article Details
How to Cite
KAOUTAR, Zirhirhi et al.
Myocardial lesions during Severe Acute Respiratory Syndrome Coronavirus 2 infection.
Medical Research Archives, [S.l.], v. 11, n. 12, dec. 2023.
ISSN 2375-1924.
Available at: <https://esmed.org/MRA/mra/article/view/4216>. Date accessed: 15 may 2024.
doi: https://doi.org/10.18103/mra.v11i12.4216.
Section
Case Reports
The Medical Research Archives grants authors the right to publish and reproduce the unrevised contribution in whole or in part at any time and in any form for any scholarly non-commercial purpose with the condition that all publications of the contribution include a full citation to the journal as published by the Medical Research Archives.
References
1. Organization WH. WHO Director-General’s remarks at the media briefing on 2019-nCoV doi: 10.1596/35731
2. Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China. JAMA. 2020;323(13):1239. doi:10.1001/jama.2020.2648
3. Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China. JAMA. 2020;323(13):1239. doi:10.1001/jama.2020.2648
4. Driggin E, Madhavan MV, Bikdeli B, Chuich T, Laracy J, Biondi-Zoccai G, Brown TS, Der Nigoghossian C, Zidar DA, Haythe J, Brodie D, Beckman JA, Kirtane AJ, Stone GW, Krumholz HM, Parikh SA. Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic. Journal of the American College of Cardiology. 2020;75(18):2352-2371. doi:10.1016/j.jacc.2020.03.031
5. Inciardi RM, Lupi L, Zaccone G, et al. Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19). JAMA Cardiol. 2020;5(7):819-824. doi:10.1001/jamacardio.2020.1096
6. Bavishi, C., Bonow, R. O., Trivedi, V., Abbott, J. D., Messerli, F. H., & Bhatt, D. L. (2020). Acute myocardial injury in patients hospitalized with COVID-19 infection: a review. Progress in cardiovascular diseases, 63(5), 682-689.
7. Badawi A, Ryoo SG. Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysis. International Journal of Infectious Diseases. 2016;49:129-133. doi:10.1016/j.ijid.2016.06.015
8. Zhu H, Rhee J-W, Cheng P, Waliany S, Chang A, Witteles RM, Maecker H, Davis MM, Nguyen PK, Wu SM. Correction to: Cardiovascular Complications in Patients with COVID-19: Consequences of Viral Toxicities and Host Immune Response. Current Cardiology Reports. 2020;22(5). doi:10.1007/s11886-020-01302-4
9. Driggin E, Madhavan MV, Bikdeli B, Chuich T, Laracy J, Biondi-Zoccai G, Brown TS, Der Nigoghossian C, Zidar DA, Haythe J, Brodie D, Beckman JA, Kirtane AJ, Stone GW, Krumholz HM, Parikh SA. Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic. Journal of the American College of Cardiology. 2020;75(18):2352-2371. doi:10.1016/j.jacc.2020.03.031
10. Guo T, Fan Y, Chen M, et al. Cardiovascular implications of fatal outcomes of patients with Coronavirus Disease 2019 (COVID 19). JAMA Cardiol 2020.doi :10.1001/jamacardio. 2020.1017
11. Maestrini, Viviana, Birtolo, Lucia Ilaria, Francone, Marco, et al. Cardiac involvement in consecutive unselected hospitalized COVID-19 population: In-hospital evaluation and one- year follow-up. International journal of cardiology, 2021, vol. 339, p. 235-242.
12. Caforio ALP, Pankuweit S, Arbustini E, Basso C, Gimeno-Blanes J, Felix SB, Fu M, Helio T, Heymans S, Jahns R, Klingel K, Linhart A, Maisch B, McKenna W, Mogensen J, Pinto YM, Ristic A, Schultheiss H-P, Seggewiss H, Tavazzi L, Thiene G, Yilmaz A, Charron P, Elliott PM. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. European Heart Journal. 2013;34(33):2636-2648. doi:10.1093/eurheartj/ eht210
13. World Health Organization. Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected. Interim guidance. Pediatria i Medycyna Rodzinna. 2020;16(1):9-26. doi:10.15557/pimr.2020.0003
14. https://www.aphp.fr/contenu/le-tocilizumab-amelioresignificativement-le-pronostic-des- patients-avec-pneumoniecovid
15. Shi S, Qin M, Shen B, et al. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. 2020;5:802-10.JAMA Cardiology . doi:10.1001/ jamacardio.2020.0950
16. Imazio M, Klingel K, Kindermann I, et al. COVID-19 pandemic and troponin: indirect myocardial injury, myocardial inflammation or myocarditisHeart. heart jornal 2020. doi:10.1136/heartjnl-2020-317186
17. Sandoval Y, Januzzi JL Jr, Jaffe AS. Cardiac Troponin for Assessment of Myocardial Injury in COVID-19: JACC Review Topic of the Week. J Am Coll Cardiol. 2020 Oct 13;76(15):1732-1741. doi: 10.1016/j.jacc.2020.08.065. PMID: 33032765
18. Inciardi RM, Lupi L, Zaccone G, et al. Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19). JAMA Cardiol. 2020 Jul 1;5(7):819-824. doi: 10.1001/ jamacardio.2020.1096. PMID: 32219357; PMCID: PMC7097841
2. Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China. JAMA. 2020;323(13):1239. doi:10.1001/jama.2020.2648
3. Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China. JAMA. 2020;323(13):1239. doi:10.1001/jama.2020.2648
4. Driggin E, Madhavan MV, Bikdeli B, Chuich T, Laracy J, Biondi-Zoccai G, Brown TS, Der Nigoghossian C, Zidar DA, Haythe J, Brodie D, Beckman JA, Kirtane AJ, Stone GW, Krumholz HM, Parikh SA. Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic. Journal of the American College of Cardiology. 2020;75(18):2352-2371. doi:10.1016/j.jacc.2020.03.031
5. Inciardi RM, Lupi L, Zaccone G, et al. Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19). JAMA Cardiol. 2020;5(7):819-824. doi:10.1001/jamacardio.2020.1096
6. Bavishi, C., Bonow, R. O., Trivedi, V., Abbott, J. D., Messerli, F. H., & Bhatt, D. L. (2020). Acute myocardial injury in patients hospitalized with COVID-19 infection: a review. Progress in cardiovascular diseases, 63(5), 682-689.
7. Badawi A, Ryoo SG. Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysis. International Journal of Infectious Diseases. 2016;49:129-133. doi:10.1016/j.ijid.2016.06.015
8. Zhu H, Rhee J-W, Cheng P, Waliany S, Chang A, Witteles RM, Maecker H, Davis MM, Nguyen PK, Wu SM. Correction to: Cardiovascular Complications in Patients with COVID-19: Consequences of Viral Toxicities and Host Immune Response. Current Cardiology Reports. 2020;22(5). doi:10.1007/s11886-020-01302-4
9. Driggin E, Madhavan MV, Bikdeli B, Chuich T, Laracy J, Biondi-Zoccai G, Brown TS, Der Nigoghossian C, Zidar DA, Haythe J, Brodie D, Beckman JA, Kirtane AJ, Stone GW, Krumholz HM, Parikh SA. Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic. Journal of the American College of Cardiology. 2020;75(18):2352-2371. doi:10.1016/j.jacc.2020.03.031
10. Guo T, Fan Y, Chen M, et al. Cardiovascular implications of fatal outcomes of patients with Coronavirus Disease 2019 (COVID 19). JAMA Cardiol 2020.doi :10.1001/jamacardio. 2020.1017
11. Maestrini, Viviana, Birtolo, Lucia Ilaria, Francone, Marco, et al. Cardiac involvement in consecutive unselected hospitalized COVID-19 population: In-hospital evaluation and one- year follow-up. International journal of cardiology, 2021, vol. 339, p. 235-242.
12. Caforio ALP, Pankuweit S, Arbustini E, Basso C, Gimeno-Blanes J, Felix SB, Fu M, Helio T, Heymans S, Jahns R, Klingel K, Linhart A, Maisch B, McKenna W, Mogensen J, Pinto YM, Ristic A, Schultheiss H-P, Seggewiss H, Tavazzi L, Thiene G, Yilmaz A, Charron P, Elliott PM. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. European Heart Journal. 2013;34(33):2636-2648. doi:10.1093/eurheartj/ eht210
13. World Health Organization. Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected. Interim guidance. Pediatria i Medycyna Rodzinna. 2020;16(1):9-26. doi:10.15557/pimr.2020.0003
14. https://www.aphp.fr/contenu/le-tocilizumab-amelioresignificativement-le-pronostic-des- patients-avec-pneumoniecovid
15. Shi S, Qin M, Shen B, et al. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. 2020;5:802-10.JAMA Cardiology . doi:10.1001/ jamacardio.2020.0950
16. Imazio M, Klingel K, Kindermann I, et al. COVID-19 pandemic and troponin: indirect myocardial injury, myocardial inflammation or myocarditisHeart. heart jornal 2020. doi:10.1136/heartjnl-2020-317186
17. Sandoval Y, Januzzi JL Jr, Jaffe AS. Cardiac Troponin for Assessment of Myocardial Injury in COVID-19: JACC Review Topic of the Week. J Am Coll Cardiol. 2020 Oct 13;76(15):1732-1741. doi: 10.1016/j.jacc.2020.08.065. PMID: 33032765
18. Inciardi RM, Lupi L, Zaccone G, et al. Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19). JAMA Cardiol. 2020 Jul 1;5(7):819-824. doi: 10.1001/ jamacardio.2020.1096. PMID: 32219357; PMCID: PMC7097841