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01 · ABSTRACT

Abstract

Objectives. Obesity and old age are commonly assumed to be risk factors for COVID-19 mortality. On a worldwide basis, we examine quantitative measures of obesity and elderly in the populations of individual countries and territories, and investigate whether these measures are predictive of COVID-19 mortality in those countries. In particular, we highlight regional differences relative to obesity and elderly metrics, and how these relate to COVID-19 mortality.

Methods. In this retrospective, population-based study, we obtained data relating to percentages of obese or elderly individuals in 199 countries, as well as COVID-19 mortality rates in these countries. We used negative binomial regression analyses to assess associations between COVID-19 mortality rates and the putative risk factors, in six regions – Africa, Asia, Europe, North America, Oceania, and South America.

Results. We found significant differences between regions relative to COVID-19 mortality, as well as obesity and elderly population proportions. There were also substantial differences between countries within regions relative to proportions of obesity and elderly individuals, and COVID-19 mortality.

Conclusions. There are significant differences both between regions and within regions relative to COVID-19 mortality rates, as well as proportions of obese or elderly individuals. A global pronouncement that obesity and elderly constitute definitive risk factors for COVID-19 mortality masks the subtleties engendered by these intra- and inter-regional differences.

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02 · PUBLICATION RECORD

Article details

JournalMedical Research Archives
IssueVol 11 No 8 (2023): August Issue, Vol.11, Issue 8
SectionResearch Articles
Published29 August 2023
DOI10.18103/mra.v11i8.4248
ISSN2375-1924
03 · RIGHTS & REUSE

Rights & reuse

This article is published under a Creative Commons Attribution License (CC BY 3.0) and may be shared or distributed by anyone as long as attribution is given to the journal.

Authors & affiliations

JK

James A. Koziol

Proteogenomics Research Institute for Systems Medicine La Jolla, California USA

JS

Jan E. Schnitzer

Proteogenomics Research Institute for Systems Medicine La Jolla, California USA

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