Kidney stones in patients with type 2 diabetes mellitus. Metabolic risk factors

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Published Oct 25, 2023
DOI: https://doi.org/10.18103/mra.v11i10.4483

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Main Article Content

Francisco Rodolfo Spivacow
Instituto de Investigaciones Metabólicas (IDIM), Buenos Aires, Argentina; Universidad del Salvador (USAL), Buenos Aires, Argentina.
Elisa Elena del Valle
Instituto de Investigaciones Metabólicas (IDIM), Buenos Aires, Argentina; Universidad del Salvador (USAL), Buenos Aires, Argentina.
Paula Rey
Instituto de Investigaciones Metabólicas (IDIM), Buenos Aires, Argentina; Universidad del Salvador (USAL), Buenos Aires, Argentina.
Pablo Martínez Allo
Instituto de Investigaciones Metabólicas (IDIM), Buenos Aires, Argentina.
Martín Pailler
Instituto de Investigaciones Metabólicas (IDIM), Buenos Aires, Argentina.

Abstract

Background: In the past few decades, the prevalence of kidney stones in Western countries has increased in parallel with the growing overweight/obesity and type 2 diabetes mellitus rates. An increased insulin resistance in these patients explains, in part, the rising prevalence of uric acid stones.


Aim: The Aim of this retrospective study was to evaluate the metabolic abnormalities in type 2 diabetic and non-diabetic patients with kidney stones.


Methods: A total of 104 diabetic patients (age: 57.8 ± 11 years) and 130 non-diabetics (age: 52.1 ± 6.7 years) with kidney stones were selected.


Results: Higher rates of body mass index, hypertension, urinary tract infection, gout and hyperuricemia were observed in diabetic patients as compared to the non-diabetics, while similar rates were found for their family history of kidney stones. Metabolic abnormalities were detected in 95.2% and 81.5% of diabetics and non-diabetics, respectively. Idiopathic hypercalciuria was the most frequent abnormality in both groups, although as a simple abnormality, in diabetic patients, unduly acidic urine was the more common.


Conclusions: unduly acidic urine is the most frequent single abnormalities in patients with diabetes mellitus and is in part responsible for the greater number of uric acid stones.

Keywords: Metabolic risk factors, kidney stone, type 2 diabetes

Article Details

How to Cite
SPIVACOW, Francisco Rodolfo et al. Kidney stones in patients with type 2 diabetes mellitus. Metabolic risk factors. Medical Research Archives, [S.l.], v. 11, n. 10, oct. 2023. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/4483>. Date accessed: 23 nov. 2024. doi: https://doi.org/10.18103/mra.v11i10.4483.
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Issue
Vol 11 No 10 (2023): October Issue, Vol.11, Issue 10
Section
Research Articles

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