Thermal Product Sensor: A potentially new diagnostic tool in the detection of skin malignancy

Main Article Content

C DeGiovanni M Patel P Drake P Sains V Sridhar Kam Chana

Abstract

Skin cancer is one of the most common cancers in the world. Skin cancer is currently a global public health problem that is escalating. In the UK, the incidence of malignant melanoma has increased from 837 per year to 6963 per year in males and 1609 per year to 6952 per year in females between 1981 and 2018. Early diagnosis and treatment, as with any other disease will have a positive outcome in terms of survival and costs of management. Advances in technology have allowed the development of tools that provide rapid and sensitive diagnosis of many diseases. This paper describes the development and use of a thermal based technique which directly measures the thermal properties of skin. The Thermal Product Sensor (TPS), a new biosensor, has been demonstrated in the diagnosis of skin malignancies. The technique is quantitative and is shown to distinguish between normal and malignant skin. The study demonstrates on 12 patients the thermal product technique successfully detected skin cancers in comparison to normal skin.

Keywords: Thermal Product Sensor: A potentially new diagnostic tool in the detection of skin malignancy, skin malignancy, diagnostic tool

Article Details

How to Cite
DEGIOVANNI, C et al. Thermal Product Sensor: A potentially new diagnostic tool in the detection of skin malignancy. Medical Research Archives, [S.l.], v. 12, n. 1, feb. 2024. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/4987>. Date accessed: 24 feb. 2024. doi: https://doi.org/10.18103/mra.v12i1.4987.
Section
Research Articles

References

1. Memon A, Bannister P, Rogers I, Sundin J, Al-Ayadhy B, James P.W, McNally RJQ. Changing epidemiology and age-specific incidence of cutaneous malignant melanoma in England; An analysis of the national cancer registration data by age, gender and anatomical site, 1981 – 2018, (2021). Lancet Reg Health Eur 2021 Jan 6:2:100024. Doi 10.1016/j.lanepe.2021.100024.

2. Losquadro WD. Anatomy of the skin and the pathogenesis of nonmelanoma skin cancer Facial Plastic Surgery Clinics, 25 (3) (2017), pp. 283-289.

3. Zhang W, Zeng W, Jiang A, He Z, Shen X, Dong X, Feng J, Lu H. Global, regional and national incidence, mortality and disability-adjusted life-years of skin cancers and trend analysis from 1990 to 2019: An analysis of the Global Burden of Disease Study 2019. Cancer Med. 2021 Jul;10(14):4905-4922. doi: 10.1002/cam4.4046. Epub 2021 Jun 9. PMID: 34105887; PMCID: PMC8290243.

4. Dorrell DN, Strowd LC. Skin Cancer Detection Technology. Dermatol Clin. 2019 Oct;37(4):527-536. doi: 10.1016/j.det.2019.05.010. Epub 2019 Jul 10. PMID: 31466592.

5. Kaube et al. Biosensors: Fundamentals and Applications. Oxford, UK: Oxford University Press. (1987) p. 770.

6. Naresh V, Lee N. A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors. Sensors (Basel). 2021;21(4):1109. Published 2021 Feb 5. doi:10.3390/s21041109.

7. Sains et al. Pilot study on an innovative biosensor with a potentially wide range of medical and surgical applications. BMC Res notes (2018) 11:81.

8. González FJ, Castillo-Martínez C, Valdes-Rodríguez R, Kolosovas-Machuca ES, Villela-Segura U, Moncada B. Thermal signature of melanoma and non-melanoma skin cancers. In: 11th International Conference on Quantitative InfraRed Thermography, Naples Italy, 11–14 June 2012.

9. Okabe T, Fujimura T, Okajima J, Kambayashi Y, Aiba S, Maruyama S. First-in-human clinical study of novel technique to diagnose malignant melanoma via thermal conductivity measurements. Sci Rep. 2019 Mar 7;9(1):3853. doi: 10.1038/s41598-019-40444-6. PMID.