Inflammation from the basics to the clinical: Advances and challenges in oxidative stress

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Published Jan 31, 2024
DOI: https://doi.org/10.18103/mra.v12i1.5072

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Main Article Content

Luis-Eder Vargas-Campos
Maestro en Ciencias; Universidad Autónoma de Guerrero, Facultad de Odontología, Laboratorio de Ciencias Básicas, Acapulco de Juárez Guerrero, México.
Marco-A. Adams-Reyes
Acapulco de Juárez Guerrero, México. 2 Especialista en Implantología Facultad Centro Oeste Paulista FACOP, Bauru Sao Paulo Brasil.
Julio-Cesar Adams-Ocampo
Maestría en Ciencias; Universidad Autónoma de Guerrero, Facultad de Odontología, Laboratorio de Ciencias Básicas, Acapulco de Juárez Guerrero, México.
Juan-Manuel Luna-Gomez
Especialista en Ortodoncia; Universidad Autónoma de Guerrero, Facultad de Odontología, Laboratorio de Ciencias Básicas, Acapulco de Juárez Guerrero, México.
Yanet Medina-Rojas
Maestra en Ciencias; Universidad Autónoma de Guerrero, Facultad de Odontología, Laboratorio de Ciencias Básicas, Acapulco de Juárez Guerrero, México.
Luis-Martin Vargas-Zuñiga
Doctor en Ciencias; Universidad Autónoma de Guerrero, Facultad de Odontología, Laboratorio de Ciencias Básicas, Acapulco de Juárez Guerrero, México.

Abstract

Introduction. - In this review, one of the mechanisms that is generated in inflammation, oxidative stress, was analyzed. Inflammation is an immune system response, it is essential for survival and recovery, but it can cause damage to the body, due to oxidative stress that occurs when there is an imbalance between the production of reactive oxygen species and the body's ability to neutralize them with Endogenous antioxidants contribute to the development of chronic diseases such as cardiovascular, diabetes, autoimmune diseases, cancer, neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis.


Aim. - Evaluate the literature about Inflammation from the basic to the clinical.


Methodology. - Databases such as MEDLINE/PubMed and ScienceDirect regarding Inflammation were analyzed.


Results. - Despite recent advances in the understanding of inflammation and oxidative stress, there are still important challenges in the study and treatment of these conditions, on the one hand, it is necessary to develop more precise biomarkers to evaluate oxidative stress and inflammation in the patients. While in the other, new therapeutic approaches are needed to modulate inflammation and oxidative stress more effectively and specifically.


Conclusion. - That the study of inflammation and oxidative stress is crucial to understanding the pathophysiological bases of various chronic diseases and that advances in the field of inflammation and oxidative stress have provided new therapeutic perspectives for the treatment and prevention of chronic diseases.

Keywords: Inflammation, oxidative stress, reactive oxygen species and chronic diseases

Article Details

How to Cite
VARGAS-CAMPOS, Luis-Eder et al. Inflammation from the basics to the clinical: Advances and challenges in oxidative stress. Medical Research Archives, [S.l.], v. 12, n. 1, jan. 2024. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/5072>. Date accessed: 21 dec. 2024. doi: https://doi.org/10.18103/mra.v12i1.5072.
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Issue
Vol 12 No 1 (2024): January Issue, Vol.12, Issue 1
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Review Articles

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