Prejudice, against GMO crops and Golden Rice, in US Academia drove unethical behaviour, with global and detrimental consequences for vitamin A deficiency alleviation.

Main Article Content

A C Dubock

Abstract

In 2015, Tang et al 2012 was retracted. The paper concerned human research, relevant to public health, conducted in China in 2008. Retraction represents the most severe criticism of a scientific article. This article recounts events over a four-year period and challenges the justification for retraction based on the Committee on Publication Ethics principles.


This research focuses on analysing contemporary (2012–2015) documentary evidence, organised by key narrative participants: Greenpeace, the Chinese Government, Tufts University, the American Society for Nutrition, the US National Institutes of Health, and the US Office for Human Research Protections.


The analysis indicates that technological bias within a university and a learned society, which is also a publisher, led to unethical behaviour and the subsequent retraction. In the USA, oversight of an Institutional Review Board falls under the Office for Human Research Protections. Despite being the principal funder, the NIH's reliance on this office for the retracted paper's research to be publicly available, suggests ineffective oversight. 


The retracted paper detailed a crucial nutritional study relevant to combating vitamin A deficiency, a significant cause of child mortality and blindness in Low- and Middle-Income countries. The retraction likely heightened suspicion around this vital public health intervention.


Recommendations are made which are designed to partially ameliorate the injustices perpetrated.

Keywords: Tufts University, ASN, AJCN, China, VAD

Article Details

How to Cite
DUBOCK, A C. Prejudice, against GMO crops and Golden Rice, in US Academia drove unethical behaviour, with global and detrimental consequences for vitamin A deficiency alleviation.. Medical Research Archives, [S.l.], v. 12, n. 2, mar. 2024. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/5091>. Date accessed: 27 apr. 2024. doi: https://doi.org/10.18103/mra.v12i2.5091.
Section
Research Articles

References

1. COPE Council. COPE Retraction guidelines — English. (2019) doi: 10.3325/cmj.2009.50.532

2. Dubock, A. The present status of Golden Rice. J Huazhong Agric Univ. 33, 69–84 (2014).

3. Editorial. Reburnishing Golden Rice. Nat Biotechnol 23, 395 (2005). https://doi.org/10.1038/nbt0405-395

4. Enserink, M. Golden Rice not so Golden for Tufts, Science Insider (2013). http://news.sciencemag.org/asiapacific/2013/09/golden-rice-not-so-golden-tufts

5. Gostin, L. O. Global Health: Shared Obligations and Mutual Respect. Ann. Glob. Heal. 85, 80 (2019)

6. Grune T., Lietz G., Palou A., Ross A. C., Stahl W., Tang G., Thurnham D., Yin S., and Biesalski H. K. β-Carotene is an important vitamin A source for humans. J. Nutr. (2010). doi: 10.3945/jn.109.119024

7. Hvistendahl, M. & Enserink, M. Charges Fly, Confusion Reigns Over Golden Rice Study in Chinese Children. Science 1281 (2012). DOI: 10.1126/science.337.6100.1281

8. Miller, H. The-Greenpeace-motto-save-the-whales-let-the- children-die. Forbes (2015). https://geneticliteracyproject.org/2015/08/11/blood-on-their-hands-withdrawal-of-golden-rice-study-for-non-science-reasons-feeds-anti-gmo-fervor/ accessed December 8 2023

9. Online document. Anon. Institutional review board. Retrieved November 13, 2023 from https://en.wikipedia.org/wiki/Institutional_review_board

10. Online document. Anon. Diane Souvaine. Retrieved November 14, 2023 from https://en.wikipedia.org/wiki/Diane_Souvaine

11. Roberts, R., et al., 2016, Laureates letter supporting precision agriculture (GMOs). https://www.supportprecisionagriculture.org/nobel-laureate-gmo-letter_rjr.html Accessed February 9 2024.

12. Stevens G.A., Beal T., Mbuya M.N.N., Luo H., Neufeld L.M. Micronutrient deficiencies among preschool-aged children and women of reproductive age worldwide: a pooled analysis of individual-level data from population-representative surveys. Lancet Global Health (10) e1590-e1599 (2022). www.thelancet.com/lancetgh

13. Tang, G. Using plant foods rich in β-carotene to combat vitamin A deficiency. Sight Life 27, (2013).

14. Tang, G., Jian, Q., Dolnikowski, G. G., Russell, R. M. & Grusak, M. A. Golden rice is an effective source of vitamin A. Am. J. Clin. Nutr. 89, 1776–1783 (2009).

15. Tang, G., Hu Y., Yin S., Wang Y., Dallal G. E., Grusak M. A., and Russell R. β -Carotene in Golden Rice is as good as β -carotene in oil at providing vitamin A to children. Am J Clin Nutr 96, 658–664 (2012).

16. Tang, G., Hu Y., Yin S., Wang Y., Dallal G. E., Grusak M. A., and Russell R. Retracted: β-Carotene in Golden Rice is as good as β-carotene in oil at providing vitamin A to children. American Journal of Clinical Nutrition (2012) 96 (658-664)). 4x egasin Ref 14 e 15 vol.102715(2015). DOI:https://doi.org/10.3945/ajcn.111.030775

17. Wu, F., Wesseler, J., Zilberman, D., Russell, R. M., Chen, C., and Dubock, A. C. Allow Golden Rice to save lives. PNAS 118, 51 https://doi.org/10.1073/pnas 2120901118 (2021).