Type 1 myocardial infarction in a 27-year-old patient with substance abuse, IGM antibodies against borrelia burgdorferi and hypercholesterolemia: Case report
Main Article Content
Abstract
Background: The overall incidence of hospital admissions because of myocardial infarction attributable to young patients seams to increase over the years. Myocardial infarction in young patients is a rare disease, it is necessary to identify young patients with a high risk profile to recognize and treat them in time.
Case Summary: We present a patient with an acute heart attack at a young age and several risk factors for a cardiovascular event, including multiple drug abuse and hypercholesterolemia. Additionally, the patient had a second-degree atrioventricular block and severely reduced pumping function in the echocardiography. Intriguing about this case is the exceptionally young age and the potential impact of the risk factors.
Discussion: This case illustrates that even young patients can experience an occlusive myocardial infarction and in the presence of cardiovascular risk factors, coronary heart disease should be considered even at a young age.
Article Details
The Medical Research Archives grants authors the right to publish and reproduce the unrevised contribution in whole or in part at any time and in any form for any scholarly non-commercial purpose with the condition that all publications of the contribution include a full citation to the journal as published by the Medical Research Archives.
References
2. Nording HM, Seizer P, Langer HF. Platelets in inflammation and atherogenesis. Front Immunol. 2015;6:98. doi:10.3389/fimmu.2015.00098
3. Lawton JS, Tamis-Holland JE, Bangalore S, et al. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. Jan 18 2022;79(2):e21-e129. doi:10.1016/j.jacc.2021.09.006
4. Gawaz M, Geisler T, Borst O. Current concepts and novel targets for antiplatelet therapy. Nat Rev Cardiol. Sep 2023;20(9):583-599. doi:10.1038/s41569-023-00854-6
5. Johansson S, Rosengren A, Young K, Jennings E. Mortality and morbidity trends after the first year in survivors of acute myocardial infarction: a systematic review. BMC Cardiovasc Disord. Feb 7 2017;17(1):53. doi:10.1186/s12872-017-0482-9
6. Shah N, Kelly AM, Cox N, Wong C, Soon K. Myocardial Infarction in the "Young": Risk Factors, Presentation, Management and Prognosis. Heart Lung Circ. Oct 2016;25(10):955-60. doi:10.1016/j.hlc.2016.04.015
7. Sagris M, Antonopoulos AS, Theofilis P, et al. Risk factors profile of young and older patients with myocardial infarction. Cardiovasc Res. Jul 27 2022;118(10):2281-2292. doi:10.1093/cvr/cvab264
8. Krittanawong C, Khawaja M, Tamis-Holland JE, Girotra S, Rao SV. Acute Myocardial Infarction: Etiologies and Mimickers in Young Patients. J Am Heart Assoc. Sep 19 2023;12(18):e029971. doi:10.1161/jaha.123.029971
9. Arora S, Stouffer GA, Kucharska-Newton AM, et al. Twenty Year Trends and Sex Differences in Young Adults Hospitalized With Acute Myocardial Infarction. Circulation. Feb 19 2019;139(8):1047-1056. doi:10.1161/circulationaha.118.037137
10. Gulati R, Behfar A, Narula J, et al. Acute Myocardial Infarction in Young Individuals. Mayo Clin Proc. Jan 2020;95(1):136-156. doi:10.1016/j.mayocp.2019.05.001
11. Jortveit J, Pripp AH, Langørgen J, Halvorsen S. Incidence, risk factors and outcome of young patients with myocardial infarction. Heart. Sep 2020;106(18):1420-1426. doi:10.1136/heartjnl-2019-316067
12. Zasada W, Bobrowska B, Plens K, et al. Acute myocardial infarction in young patients. Kardiol Pol. 2021;79(10):1093-1098. doi:10.33963/KP.a2021.0099
13. Yang J, Biery DW, Singh A, et al. Risk Factors and Outcomes of Very Young Adults Who Experience Myocardial Infarction: The Partners YOUNG-MI Registry. Am J Med. May 2020;133(5):605-612.e1. doi:10.1016/j.amjmed.2019.10.020
14. Richards JR, Bing ML, Moulin AK, et al. Cannabis use and acute coronary syndrome. Clin Toxicol (Phila). Oct 2019;57(10):831-841. doi:10.1080/15563650.2019.1601735
15. Li XR, Zuo HJ, Yang HX, et al. [Clinical characteristics and prognosis of young (<35 years) patients with acute ST-segment elevation myocardial infarction]. Zhonghua Xin Xue Guan Bing Za Zhi. Nov 24 2021;49(11):1124-1129. doi:10.3760/cma.j.cn112148-20210805-00672
16. Ray KK, Ference BA, Séverin T, et al. World Heart Federation Cholesterol Roadmap 2022. Glob Heart. 2022;17(1):75. doi:10.5334/gh.1154
17. Delgado GE, Krämer BK, Siekmeier R, et al. Influence of smoking and smoking cessation on biomarkers of endothelial function and their association with mortality. Atherosclerosis. Jan 2020;292:52-59. doi:10.1016/j.atherosclerosis.2019.11.017
18. Robert-Koch-Institut. Lyme-Borreliose. RKI-Ratgeber. Accessed 03.04.2023, https://www.rki.de/DE/Content/Infekt/EpidBull/Merkblaetter/Ratgeber_LymeBorreliose.html#doc2398672bodyText6
19. Institut RK. Lyme-Borreliose. Accessed 03.04.2023, https://www.rki.de/DE/Content/Infekt/EpidBull/Merkblaetter/Ratgeber_LymeBorreliose.html#doc2398672bodyText6